{"id":"W1964384703","doi":"10.4161/epi.23063","title":"Tissue-specific relationship of S-adenosylhomocysteine with allele-specific<i>H19/Igf2</i>methylation and imprinting in mice with hyperhomocysteinemia","year":2012,"lang":"en","type":"article","venue":"Epigenetics","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Child and Family Research Institute; University of British Columbia; Canadian Institutes of Health Research; Sick Kids Foundation; Heart and Stroke Foundation of Canada; American Heart Association","keywords":"Methylation; Genomic imprinting; Imprinting (psychology); Biology; Hyperhomocysteinemia; DNA methylation; Cystathionine beta synthase; Homocysteine; Allele; Methyltransferase; Molecular biology; Gene expression; Endocrinology; Gene; Genetics; Methionine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000130279,0.000422116,0.0003352386,0.001027217,0.0002007613,0.0004246882,0.0002742616,0.0004234825,0.002364941],"category_scores_gemma":[0.0001284572,0.0004111526,0.0003110473,0.0002668488,0.0004942841,0.0002080524,0.0002504973,0.001076666,0.0004190461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005493687,"about_ca_system_score_gemma":0.0002451476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001997657,"about_ca_topic_score_gemma":0.003065643,"domain_scores_codex":[0.9997086,0.00003078327,0.00002390242,0.0000959742,0.00006890391,0.00007179612],"domain_scores_gemma":[0.9994117,0.00005747068,0.0002359907,0.00003404012,0.00002941659,0.0002312996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004379417,0.00002589188,0.0007035796,0.00001000656,0.000006283883,0.00004367223,0.000019585,0.00002337925,0.9980349,0.00004321253,0.00001737567,0.0006341653],"study_design_scores_gemma":[0.00003754423,0.0005949262,0.03866488,0.000006139657,0.00004420738,0.0004265037,0.00007995706,0.0004573226,0.9586115,0.00006867867,0.0009952013,0.00001302226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963916,0.0007581976,0.001077835,0.0001013168,0.00001933342,0.00001219093,0.0006214508,0.000114139,0.0009039546],"genre_scores_gemma":[0.9917082,0.0005120651,0.001202207,0.00007616114,0.0000127005,0.00003490411,0.0007178769,0.0001019877,0.005633896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002364941,"threshold_uncertainty_score":0.007911503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0166435731230727,"score_gpt":0.2333007787405293,"score_spread":0.2166572056174566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}