{"id":"W1964520385","doi":"10.1371/journal.pgen.1000775","title":"Mobile Antibiotic Resistance Encoding Elements Promote Their Own Diversity","year":2009,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Fonds Québécois de la Recherche sur la Nature et les Technologies; Howard Hughes Medical Institute","keywords":"Mobile genetic elements; Biology; Vibrio cholerae; Genetics; Genome; Integrases; Gene; Horizontal gene transfer; Recombination; Antibiotic resistance; Homologous recombination; Genetic recombination; Host (biology); Computational biology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001328927,0.0002369509,0.0002018144,0.00003752991,0.0003162121,0.00006152492,0.0004538737,0.000159906,0.00002519048],"category_scores_gemma":[0.00004307241,0.0002265137,0.00009060134,0.0001129434,0.0001106522,0.000005399636,0.0002900196,0.00009955443,0.00002128765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000335374,"about_ca_system_score_gemma":0.0000547765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":6.149811e-7,"about_ca_topic_score_gemma":0.00001422641,"domain_scores_codex":[0.9985435,0.00005363566,0.0002801163,0.0004908415,0.0002220664,0.0004098338],"domain_scores_gemma":[0.9990103,0.000006311331,0.0001483922,0.0006244847,0.0001025667,0.0001078947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007496871,0.0001980515,0.03467368,0.00003659585,0.0000651887,0.000008691289,0.0002003688,0.00001211179,0.9620544,0.00002481385,0.001158914,0.001492195],"study_design_scores_gemma":[0.000440646,0.0005135092,0.0125669,0.00007031133,0.00004278588,0.000003694576,0.00009339841,0.0001057803,0.9673995,0.0002414332,0.01814316,0.000378824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946923,0.001282894,0.0002205241,0.00004238086,0.0001286851,0.0003898678,0.00003906007,0.00003244968,0.003171857],"genre_scores_gemma":[0.993804,0.0006422944,0.0037683,0.0002088023,0.0002049808,0.000001763725,0.00006447535,0.00002322185,0.001282147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02210679,"threshold_uncertainty_score":0.9236962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01526106766277776,"score_gpt":0.2399393578246763,"score_spread":0.2246782901618986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}