{"id":"W1964527234","doi":"10.1016/j.neurobiolaging.2009.06.001","title":"Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide","year":2009,"lang":"en","type":"article","venue":"Neurobiology of Aging","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":201,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Fondation pour la Recherche sur Alzheimer","keywords":"Cystathionine beta synthase; Neuroprotection; Microglia; Chemistry; Hydroxylamine; Astrocyte; Biochemistry; Cell culture; Endogeny; Pharmacology; Enzyme; Molecular biology; Cell biology; Inflammation; Biology; Cysteine; Immunology; Endocrinology; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002214864,0.0001652755,0.0001786692,0.00004392518,0.0001099734,0.000007360778,0.0002708859,0.0001040626,0.00000276343],"category_scores_gemma":[0.0001161419,0.0001235163,0.00006012458,0.0000670614,0.0003614268,0.000003282744,0.0001567494,0.0001640927,0.000002618882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004977653,"about_ca_system_score_gemma":0.00003109523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000467637,"about_ca_topic_score_gemma":0.000002971216,"domain_scores_codex":[0.9988195,0.0002238696,0.0002135438,0.0004387451,0.00004573071,0.0002586435],"domain_scores_gemma":[0.9993239,0.00004851599,0.0001335581,0.0004009817,0.00005710549,0.00003591161],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005492835,0.00002046079,0.006443277,0.00000534932,0.00002870102,0.000003555818,0.00006196911,0.00004030185,0.9911065,0.00008085177,0.0001488345,0.00200528],"study_design_scores_gemma":[0.0002687367,0.000635671,0.06061698,0.000008075819,0.00001514329,0.0001284977,0.00003344888,0.00001221234,0.9340584,0.0001344935,0.003962462,0.000125821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973745,0.001023757,0.00005567453,0.0008763333,0.0001523951,0.0002318421,0.000003855216,0.00001998918,0.0002615962],"genre_scores_gemma":[0.9984445,0.000193587,0.0002260345,0.0008758641,0.0001755305,0.000008244207,0.00001133,0.00001237063,0.00005256592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05704804,"threshold_uncertainty_score":0.5036849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008641045863302279,"score_gpt":0.2294279025625276,"score_spread":0.2207868566992253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}