{"id":"W1964528652","doi":"10.2174/13816128113199990558","title":"Heme Oxygenase System and Hypertension: A Comprehensive Insight","year":2014,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Heme oxygenase; Cytoprotection; Medicine; Oxidative stress; Heme; Biliverdin; Cyclic guanosine monophosphate; Inflammation; Hemin; Soluble guanylyl cyclase; Pathophysiology; Internal medicine; Pharmacology; Endocrinology; Biology; Nitric oxide; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006096323,0.0006104387,0.0008763207,0.002263263,0.0003837746,0.001508314,0.0005704081,0.001254843,0.002971403],"category_scores_gemma":[0.0005487559,0.0002506246,0.0005038348,0.001493675,0.0008628782,0.002520459,0.00123565,0.002409478,0.0006092884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008176273,"about_ca_system_score_gemma":0.001427321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002035514,"about_ca_topic_score_gemma":0.002398763,"domain_scores_codex":[0.9998327,0.00003982069,0.00002315069,0.00003130478,0.00004685911,0.00002608692],"domain_scores_gemma":[0.9996651,0.0001617228,0.0000449288,0.00001276879,0.00006789379,0.00004753013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002796774,0.0003602372,0.004602579,0.007754485,0.0002917949,0.001951174,0.0006292636,0.0007209405,0.003780269,0.02230423,0.0521909,0.9051344],"study_design_scores_gemma":[0.00005142745,0.0006571505,0.02498031,0.008513544,0.0004114488,0.01100173,0.001112749,0.001230449,0.0008827725,0.05627951,0.8947579,0.0001209045],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001000553,0.992457,0.0004140463,0.004544349,0.0003373991,0.000006461154,0.0000345037,0.0000127421,0.001192915],"genre_scores_gemma":[0.006968688,0.9876123,0.0006767337,0.001776154,0.001878917,0.00001151864,0.00005944319,0.000003655442,0.00101258],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002971403,"threshold_uncertainty_score":0.009940386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1484916792865824,"score_gpt":0.3776335588832804,"score_spread":0.2291418795966981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}