{"id":"W1964528652","doi":"10.2174/13816128113199990558","title":"Heme Oxygenase System and Hypertension: A Comprehensive Insight","year":2014,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Heme oxygenase; Cytoprotection; Medicine; Oxidative stress; Heme; Biliverdin; Cyclic guanosine monophosphate; Inflammation; Hemin; Soluble guanylyl cyclase; Pathophysiology; Internal medicine; Pharmacology; Endocrinology; Biology; Nitric oxide; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003294666,0.0007880781,0.001579279,0.0001162152,0.0001304188,0.00007435151,0.0003736061,0.0005107619,0.00001944922],"category_scores_gemma":[0.00007951747,0.0006287472,0.0004939697,0.0001755321,0.0001915662,0.000004834902,0.0003241882,0.0005551793,0.0001514833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005558895,"about_ca_system_score_gemma":0.0002463291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":7.905734e-7,"about_ca_topic_score_gemma":1.377087e-7,"domain_scores_codex":[0.9964414,0.0008588344,0.0007448524,0.00107328,0.0002846595,0.0005970236],"domain_scores_gemma":[0.9981965,0.0001447016,0.0002267255,0.0006428564,0.0001496019,0.0006396183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005734929,0.0001180426,6.223908e-7,0.02055478,0.0002956842,0.00007273736,0.000007286919,0.000001499292,0.002226605,0.000230114,0.01091295,0.9655223],"study_design_scores_gemma":[0.0006173406,0.0001586782,7.289527e-7,0.003360632,0.000854691,0.0003555832,0.000007198544,0.0003622196,0.0008486012,0.000003670458,0.9927097,0.0007209497],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005840895,0.9931796,0.004318939,0.00001604447,0.0009102157,0.00116304,0.00005090104,0.00006461714,0.0002382658],"genre_scores_gemma":[0.0006351303,0.9971234,0.0003022417,0.0002166756,0.001006247,0.0002074526,0.0003066313,0.0001110102,0.00009119904],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9817967,"threshold_uncertainty_score":0.9996164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1484916792865824,"score_gpt":0.3776335588832804,"score_spread":0.2291418795966981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}