{"id":"W1964581555","doi":"10.1016/j.regpep.2006.04.023","title":"Involvement of multiple signaling pathways in PACAP-induced EM66 secretion from chromaffin cells","year":2006,"lang":"en","type":"article","venue":"Regulatory Peptides","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"","keywords":"Chelerythrine; BAPTA; Adrenal medulla; Chromaffin cell; Endocrinology; Secretion; Internal medicine; Protein kinase C; Channel blocker; Pituitary adenylate cyclase-activating peptide; Calcium channel blocker; Adrenal gland; Protein kinase A; Signal transduction; MAPK/ERK pathway; Chemistry; Biology; Cell biology; Kinase; Calcium; Receptor; Neuropeptide; Catecholamine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000241279,0.000573507,0.0004415355,0.0002701083,0.0004133758,0.0006154355,0.0002314769,0.0003740844,0.002135694],"category_scores_gemma":[0.0001918585,0.0002125798,0.0005332527,0.0002192482,0.0001922029,0.001024717,0.0005871853,0.001011322,0.00048223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003670907,"about_ca_system_score_gemma":0.0003729387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004333034,"about_ca_topic_score_gemma":0.0004758668,"domain_scores_codex":[0.9998282,0.00002186738,0.00001850982,0.00002834602,0.00003360964,0.00006943766],"domain_scores_gemma":[0.9998852,0.00002294226,0.00001637344,0.00001172441,0.0000177814,0.00004603931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005719471,0.00003898762,0.0003285205,0.00008361696,0.00001069652,0.0004388432,0.00002338333,0.00005177655,0.9953257,0.00027022,0.00003645959,0.002819874],"study_design_scores_gemma":[0.0000508637,0.0002305588,0.01686692,0.00001644457,0.00003945653,0.000529513,0.0001222373,0.0007832856,0.9796742,0.000195702,0.001479772,0.00001105072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811646,0.005147426,0.009014995,0.0003725025,0.0001083793,0.00007512008,0.0004827227,0.00007975197,0.00355444],"genre_scores_gemma":[0.9879491,0.002258509,0.00483242,0.0001287845,0.00004091607,0.00008407835,0.0004946527,0.00001956157,0.004191957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002135694,"threshold_uncertainty_score":0.00714463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03771136652735827,"score_gpt":0.2270090623428573,"score_spread":0.189297695815499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}