{"id":"W1964593378","doi":"10.1038/ncponc0425","title":"Are prostate cancer clinical trial enrollment criteria and endpoints appropriate?","year":2006,"lang":"en","type":"article","venue":"Nature Clinical Practice Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre","funders":"","keywords":"Prostate cancer; Medicine; Cancer; Prostate; Clinical trial; Oncology; Medical physics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00477898,0.0002995339,0.001193472,0.0001035716,0.0001645594,0.0000593626,0.0001566907,0.001657609,0.0003169641],"category_scores_gemma":[0.01046184,0.0002114065,0.0002872464,0.0002264035,0.0006749093,0.0002545347,0.0001989046,0.003720738,0.00007769524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003059694,"about_ca_system_score_gemma":0.001087291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000102141,"about_ca_topic_score_gemma":0.0001049639,"domain_scores_codex":[0.9948204,0.001482094,0.001587821,0.000971047,0.0005434884,0.0005952151],"domain_scores_gemma":[0.9923899,0.005087135,0.001039383,0.000462031,0.0005787491,0.0004428264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.4885797,0.0120596,0.09153347,0.0001912568,0.0009713724,0.003735242,0.000100909,7.358096e-7,0.000177373,0.000575172,0.1336235,0.2684517],"study_design_scores_gemma":[0.1289453,0.007324455,0.1366289,0.00009229303,0.0007297335,0.0001568506,0.0002296546,0.00004051814,0.00007238174,0.0009923215,0.7245384,0.0002492311],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8468581,0.01929647,0.00000938117,0.1019178,0.006848838,0.003690151,0.00006535993,0.0001370948,0.02117678],"genre_scores_gemma":[0.9500878,0.01217661,0.005192721,0.01581182,0.008851311,0.0004212102,0.0001054604,0.00007433814,0.007278709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5909149,"threshold_uncertainty_score":0.9996384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1115538585859341,"score_gpt":0.5612569716889142,"score_spread":0.4497031131029801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}