{"id":"W1964634933","doi":"10.1007/s10571-011-9671-8","title":"Akt as a Victim, Villain and Potential Hero in Parkinson’s Disease Pathophysiology and Treatment","year":2011,"lang":"en","type":"article","venue":"Cellular and Molecular Neurobiology","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"Columbia College","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Protein kinase B; Neuroscience; Disease; Parkinson's disease; Pathophysiology; Neuron; Neurodegeneration; Neuroprotection; Medicine; Signal transduction; Biology; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004360154,0.0002655927,0.0003766923,0.0001206092,0.00006250729,0.000009016149,0.00003488149,0.0001222478,0.00004061079],"category_scores_gemma":[0.00001623285,0.0002164799,0.00007203249,0.00005719763,0.0001537646,0.00002511246,0.00007934643,0.00008521372,0.000008920641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002216545,"about_ca_system_score_gemma":0.00004728322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001118492,"about_ca_topic_score_gemma":0.00000798027,"domain_scores_codex":[0.9986889,0.0001586998,0.0001732457,0.0006154681,0.00004755452,0.0003161013],"domain_scores_gemma":[0.9993265,0.0000148316,0.00004704994,0.0002278811,0.00001699025,0.0003667223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003412111,0.001522459,0.04884206,0.0001165252,0.0003465746,0.02508192,0.0007085034,0.000002137903,0.8981889,0.001326658,0.00001571006,0.02043641],"study_design_scores_gemma":[0.0318392,0.01515383,0.7008618,0.0001738753,0.002354069,0.001657046,0.0004033508,0.0008138432,0.1987974,0.0159092,0.03036853,0.001667939],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951297,0.003777071,0.0001029445,0.0001646703,0.00009134658,0.0004514727,0.00002094872,0.00002729645,0.0002345382],"genre_scores_gemma":[0.997125,0.001547651,0.0001992351,0.0008923981,0.00002327695,0.00006039222,0.00006371804,0.00002762931,0.00006068479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6993915,"threshold_uncertainty_score":0.8827793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01009459363438344,"score_gpt":0.2157436215032726,"score_spread":0.2056490278688891,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}