{"id":"W1964739661","doi":"10.1111/j.1349-7006.2008.00779.x","title":"Identification of <i>SMURF1</i> as a possible target for 7q21.3‐22.1 amplification detected in a pancreatic cancer cell line by in‐house array‐based comparative genomic hybridization","year":2008,"lang":"en","type":"article","venue":"Cancer Science","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Pancreas Research Foundation of Japan; University of Tokyo; Japan Society for the Promotion of Science; Core Research for Evolutional Science and Technology; Japan Science and Technology Corporation; University of Toronto","keywords":"Comparative genomic hybridization; Biology; Gene duplication; Copy-number variation; Gene; Gene knockdown; Fluorescence in situ hybridization; Gene dosage; Genetics; Molecular biology; Ectopic expression; Cancer research; Gene expression; Genome; Computational biology; Chromosome","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001976561,0.0001084496,0.0001497299,0.00008165336,0.000114717,0.00001975966,0.0002311342,0.00005027495,0.00001401184],"category_scores_gemma":[0.0000353333,0.0001143746,0.00002839868,0.0004260419,0.0001821813,0.00002840801,0.0000194003,0.00003766582,0.000001445268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001711044,"about_ca_system_score_gemma":0.0008111558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001026131,"about_ca_topic_score_gemma":0.0004811725,"domain_scores_codex":[0.9989247,0.00002972934,0.0003613888,0.0003533395,0.0001241158,0.0002066764],"domain_scores_gemma":[0.9992465,0.00001446574,0.0002360225,0.0002210487,0.0002371848,0.00004478282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005801451,0.00007384339,0.01492813,0.00002988908,0.000003543807,1.205314e-7,0.0004802214,0.01130219,0.9729738,0.00001885672,0.00008669904,0.0000446888],"study_design_scores_gemma":[0.0005570504,0.0001068736,0.02198816,0.00001860026,0.000007815826,0.000001115191,0.000170296,0.006007433,0.9707329,0.00004378894,0.0002335278,0.0001324989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854345,0.001094635,0.01268317,0.00004609685,0.00009552683,0.0004381615,0.0001439926,0.000008933596,0.00005492167],"genre_scores_gemma":[0.99797,0.0003990966,0.0008625407,0.00006157708,0.00003312108,0.0003855682,0.00008366875,0.00001173393,0.0001926913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01253544,"threshold_uncertainty_score":0.466406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01718063233852363,"score_gpt":0.2719398149860063,"score_spread":0.2547591826474827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}