{"id":"W1964739661","doi":"10.1111/j.1349-7006.2008.00779.x","title":"Identification of <i>SMURF1</i> as a possible target for 7q21.3‐22.1 amplification detected in a pancreatic cancer cell line by in‐house array‐based comparative genomic hybridization","year":2008,"lang":"en","type":"article","venue":"Cancer Science","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Pancreas Research Foundation of Japan; University of Tokyo; Japan Society for the Promotion of Science; Core Research for Evolutional Science and Technology; Japan Science and Technology Corporation; University of Toronto","keywords":"Comparative genomic hybridization; Biology; Gene duplication; Copy-number variation; Gene; Gene knockdown; Fluorescence in situ hybridization; Gene dosage; Genetics; Molecular biology; Ectopic expression; Cancer research; Gene expression; Genome; Computational biology; Chromosome","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001951694,0.0004047899,0.0004347401,0.0003727695,0.0001852515,0.0002994176,0.000255394,0.0003209763,0.0009522774],"category_scores_gemma":[0.0002265233,0.0001817205,0.0003122816,0.0002279479,0.0001845513,0.0001217759,0.0001597211,0.0003252898,0.0003546256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002676923,"about_ca_system_score_gemma":0.000140822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008920922,"about_ca_topic_score_gemma":0.001221121,"domain_scores_codex":[0.9998212,0.00002446527,0.00001037773,0.00005610264,0.00005362702,0.000034231],"domain_scores_gemma":[0.9998764,0.00003810152,0.00003402848,0.00001705195,0.00001755916,0.0000169554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001394546,0.000003238768,0.0002831471,0.000009060966,0.000002983149,0.00005020453,0.000006859061,0.0000271497,0.9991139,0.00001827153,0.00001561216,0.0004556803],"study_design_scores_gemma":[0.00000532984,0.0001042182,0.01590164,0.000002059207,0.00002387022,0.0005377376,0.00001668492,0.0008800647,0.9809518,0.00002266337,0.001550169,0.000003706456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856102,0.0009769253,0.01091485,0.00008735618,0.00001729324,0.00005361848,0.000737373,0.0002442043,0.001358268],"genre_scores_gemma":[0.9866807,0.0005877131,0.009481556,0.00007071974,0.000009878617,0.00009651863,0.001573295,0.00005678601,0.001442773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009522774,"threshold_uncertainty_score":0.003185689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01718063233852363,"score_gpt":0.2719398149860063,"score_spread":0.2547591826474827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}