{"id":"W1964743651","doi":"10.4161/epi.6.1.13393","title":"Global DNA methylation levels in girls with and without a family history of breast cancer","year":2011,"lang":"en","type":"article","venue":"Epigenetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cancer Care Ontario; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"National Institute of Environmental Health Sciences; Breast Cancer Research Foundation; National Cancer Institute; Foundation for the National Institutes of Health","keywords":"DNA methylation; Biology; Methylation; Family history; Breast cancer; Cancer; Pyrosequencing; Alu element; Epigenetics; Genetics; Oncology; Physiology; Internal medicine; DNA; Gene; Gene expression; Medicine; Genome; Human genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001613825,0.0001420416,0.0001677566,0.00004557539,0.00001490396,0.000003833724,0.00009009233,0.0001318952,0.00001973677],"category_scores_gemma":[0.00001346009,0.0001315541,0.0000282686,0.00009189819,0.000125925,0.000004020192,0.00004753406,0.00004351195,6.093101e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006664477,"about_ca_system_score_gemma":0.0001918116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003823693,"about_ca_topic_score_gemma":0.0008023712,"domain_scores_codex":[0.9991262,0.00006023846,0.0002404155,0.0002746043,0.0001275102,0.0001710449],"domain_scores_gemma":[0.9994559,0.000004747249,0.0001326159,0.0002268194,0.0001128793,0.00006698403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001214158,0.00006325876,0.651055,0.00002480703,0.0000357752,8.923074e-7,0.0003074357,0.0001505333,0.3378116,0.00006732631,0.00002920489,0.01033271],"study_design_scores_gemma":[0.0005748218,0.0002075226,0.9217798,0.00002184321,0.00002743873,0.000002318262,0.0000324034,0.0000741674,0.07556702,0.0002254036,0.001317296,0.0001700122],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847181,0.009231953,0.003422725,0.0000162339,0.0001129019,0.0001583267,0.00006072995,0.000004979289,0.002274022],"genre_scores_gemma":[0.9950496,0.000975644,0.003642675,0.0000421201,0.0000499143,0.00001468066,0.00001299031,0.00001761455,0.0001947477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2707247,"threshold_uncertainty_score":0.5364622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03332891525284917,"score_gpt":0.2654883678414698,"score_spread":0.2321594525886206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}