{"id":"W1964780622","doi":"10.1158/1055-9965.epi-10-0400","title":"Serum IGF-I, IGF-II, IGFBP-3, and IGF-I/IGFBP-3 Molar Ratio and Risk of Pancreatic Cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial","year":2010,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Institutes of Health","keywords":"Medicine; Internal medicine; Odds ratio; Quartile; Pancreatic cancer; Insulin-like growth factor; Gastroenterology; Confidence interval; Case-control study; Endocrinology; Cancer; Oncology; Growth factor; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00358434,0.0004337305,0.001118197,0.0002735838,0.0003426078,0.00002306908,0.0001580368,0.0005181778,0.0001400267],"category_scores_gemma":[0.001356392,0.0003205887,0.0001548524,0.0004080909,0.0007419006,0.000315656,0.0001264439,0.000807357,5.334047e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001105264,"about_ca_system_score_gemma":0.0003946464,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009285932,"about_ca_topic_score_gemma":0.007681905,"domain_scores_codex":[0.9961269,0.001102033,0.001141995,0.0007972729,0.0002059219,0.0006258877],"domain_scores_gemma":[0.9974521,0.0009513149,0.0008085679,0.0003774338,0.0001754913,0.000235035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0125978,0.0001166693,0.9511964,0.0002528573,0.0008996379,0.000007179101,0.001275088,0.00000719127,0.007189364,0.00011447,0.002153573,0.02418973],"study_design_scores_gemma":[0.01909108,0.001031283,0.9718935,0.0004865256,0.001270132,0.00003179651,0.0004039912,0.00253792,0.0009454818,0.001046595,0.0009239207,0.000337705],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9675231,0.02511415,0.0001945829,0.003618782,0.0006676026,0.00259018,0.000169558,0.00003878308,0.00008329265],"genre_scores_gemma":[0.9751729,0.02194588,0.0008509795,0.0005307005,0.0003244386,0.0009006028,0.00006284055,0.00004182171,0.000169835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02385203,"threshold_uncertainty_score":0.9999246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02504798463476975,"score_gpt":0.3331706784919387,"score_spread":0.3081226938571689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}