{"id":"W1964783496","doi":"10.1016/s0736-0266(00)90008-1","title":"Use of synovial fluid markers of cartilage synthesis and turnover to study effects of repeated intra‐articular administration of methylprednisolone acetate on articular cartilage in vivo","year":2001,"lang":"en","type":"article","venue":"Journal of Orthopaedic Research®","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Cegep de Saint Hyacinthe","funders":"","keywords":"Aggrecan; Methylprednisolone acetate; Synovial fluid; Cartilage; Keratan sulfate; Procollagen peptidase; Osteoarthritis; In vivo; Chemistry; Medicine; Andrology; Internal medicine; Endocrinology; Pathology; Methylprednisolone; Proteoglycan; Anatomy; Articular cartilage; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002730314,0.0001900391,0.0009788999,0.0008833389,0.00003201221,0.0000120876,0.0001082324,0.0001134137,0.00005684597],"category_scores_gemma":[0.003489117,0.0001497446,0.0002274777,0.0007643866,0.0002019377,0.0001856202,0.00006389499,0.000285172,7.779724e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007412217,"about_ca_system_score_gemma":0.0002132671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005848656,"about_ca_topic_score_gemma":0.0001038154,"domain_scores_codex":[0.9959369,0.0007836396,0.001282433,0.0002412149,0.001414461,0.0003413369],"domain_scores_gemma":[0.9971917,0.0008866522,0.0005168986,0.0003907428,0.0007162731,0.0002976934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01455742,0.001945943,0.02571424,0.0003416818,0.0002137815,0.002939861,0.001128018,0.00003294785,0.9478009,0.00001296795,0.0000417313,0.00527055],"study_design_scores_gemma":[0.004924159,0.02863036,0.0249724,0.001406157,0.0004303868,0.0001361166,0.000731483,0.00002947133,0.9386053,0.00002188375,0.0000266632,0.00008561645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979966,0.000446094,0.00004245199,0.0001823875,0.00007826122,0.001193715,0.00001216346,0.00000429651,0.00004403428],"genre_scores_gemma":[0.9991583,0.0002296222,0.0004656247,0.00001057652,0.00003667499,0.00002034085,0.000001313312,0.00002379905,0.00005377074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02668442,"threshold_uncertainty_score":0.6106407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03616347814892044,"score_gpt":0.3223740974779851,"score_spread":0.2862106193290646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}