{"id":"W1964854114","doi":"10.1016/s0735-1097(13)61819-7","title":"GLYCOGEN SYNTHASE KINASE–3β INHIBITION DECREASES ENDOTHELIAL PROGENITOR CELL APOPTOSIS VIA CATHEPSIN B TO ENHANCE THERAPEUTIC PROGENITOR CELL THERAPY IN PATIENTS WITH DIABETES","year":2013,"lang":"en","type":"article","venue":"Journal of the American College of Cardiology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Ottawa","funders":"","keywords":"Medicine; GSK-3; Progenitor cell; Endothelial progenitor cell; Glycogen synthase; Cancer research; Diabetes mellitus; Progenitor; Apoptosis; GSK3B; Cell biology; Pharmacology; Glycogen; Kinase; Stem cell; Internal medicine; Endocrinology; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001980265,0.0002104466,0.0005196497,0.0001635027,0.0001250846,0.0003285839,0.0001647803,0.0001876655,0.001106284],"category_scores_gemma":[0.0001581235,0.0001007729,0.0002523544,0.0001625796,0.0001577114,0.0001273074,0.0001270279,0.0008801042,0.0001213021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001454126,"about_ca_system_score_gemma":0.0002499869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00019676,"about_ca_topic_score_gemma":0.0004008647,"domain_scores_codex":[0.9999422,0.00001590827,0.000005489635,0.00000904245,0.000009556697,0.00001780876],"domain_scores_gemma":[0.9999623,0.000007339216,0.000008877216,0.000004246976,0.000002968961,0.00001432319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.04634712,0.007002418,0.008745643,0.0005062748,0.000387034,0.0008353253,0.0001507844,0.0008827595,0.7579845,0.0008266976,0.002218856,0.1741126],"study_design_scores_gemma":[0.03316714,0.1028729,0.118532,0.0001829104,0.002109659,0.005641991,0.0004587552,0.008456294,0.7020488,0.00139203,0.02505943,0.00007806795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955954,0.002885068,0.0005196444,0.000158123,0.00004189868,0.00002873687,0.00004555955,0.00003492176,0.0006907753],"genre_scores_gemma":[0.9976794,0.001226762,0.0004304236,0.00008399875,0.00002003756,0.00003745281,0.0000852929,0.000004670883,0.0004320915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001106284,"threshold_uncertainty_score":0.003700912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002828275491370252,"score_gpt":0.2022078093290411,"score_spread":0.1993795338376708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}