{"id":"W1964909656","doi":"10.1371/journal.pone.0008420","title":"Dissecting the Signaling Events That Impact Classical Nuclear Import and Target Nuclear Transport Factors","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; McGill University; Heart and Stroke Foundation of Canada","keywords":"Nucleoporin; Nuclear transport; Cell biology; Nuclear pore; Importin; Nuclear localization sequence; Nuclear export signal; Kinase; Cytoplasm; Signal transduction; Subcellular localization; Biology; Phosphorylation; Retrograde signaling; Chemistry; Cell nucleus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008448776,0.0001485279,0.0001521941,0.00001914843,0.0001851948,0.0000222291,0.0001041354,0.000127661,0.0000888839],"category_scores_gemma":[0.00002642227,0.0001007132,0.00009480479,0.00004616865,0.00003666386,0.000008655857,0.00002060864,0.000163623,0.000003865711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001148656,"about_ca_system_score_gemma":0.00001008867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009677306,"about_ca_topic_score_gemma":0.000002217466,"domain_scores_codex":[0.9992326,0.00002067011,0.0001248635,0.0002452652,0.0001685175,0.0002080742],"domain_scores_gemma":[0.9996225,0.000007234395,0.00006051778,0.000192397,0.00002931371,0.00008809452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001485912,0.0001770255,0.07309452,0.00001048514,0.0001902683,0.00000279342,0.0002948015,0.000007950133,0.9256188,0.00005230764,0.0001318695,0.0002706191],"study_design_scores_gemma":[0.0007962735,0.001699023,0.8438939,0.00007465511,0.0002977169,0.00002407607,0.0008699437,0.0004035007,0.1472033,0.0007026441,0.003444717,0.000590238],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989319,0.00008185817,0.00001314242,0.0002226264,0.0000444371,0.0001251064,0.000009293324,0.00002689934,0.000544705],"genre_scores_gemma":[0.9990436,0.00003855573,0.0002601911,0.0002260806,0.0002509261,6.89941e-7,0.00004577333,0.00002899646,0.0001051494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7784154,"threshold_uncertainty_score":0.4106964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01935246576494861,"score_gpt":0.2198855557562631,"score_spread":0.2005330899913145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}