{"id":"W1964935500","doi":"10.1016/s0005-2736(02)00493-5","title":"Determination of membrane protein topology by red-edge excitation shift analysis: application to the membrane-bound colicin E1 channel peptide","year":2002,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Colicin; Chemistry; Tripeptide; Liposome; Peptide; Membrane topology; Membrane; Lipid bilayer; Phosphatidylcholine; Vesicle; Phosphatidylglycerol; Bilayer; Crystallography; Membrane protein; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002682277,0.0002878782,0.0002892637,0.0003243654,0.0003474207,0.0004048144,0.0002469624,0.0004872002,0.0007640087],"category_scores_gemma":[0.0005011731,0.0002309493,0.0001737395,0.0002686045,0.0004095251,0.000316582,0.0002276401,0.000856777,0.0002294194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002341979,"about_ca_system_score_gemma":0.0001461275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006124332,"about_ca_topic_score_gemma":0.0007518346,"domain_scores_codex":[0.9999011,0.00001955633,0.000004391657,0.0000285433,0.00003121503,0.00001514997],"domain_scores_gemma":[0.9996767,0.0001368524,0.00004036259,0.00003433198,0.00005817453,0.00005358604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005804189,0.000007084867,0.0001280891,0.00003142945,0.00000164769,0.00002659739,0.00001471524,0.0001341444,0.9974858,0.00007478292,0.00001428281,0.002023385],"study_design_scores_gemma":[0.000007946956,0.00003352043,0.002487063,0.000004228102,0.000005632748,0.0003037362,0.00004449957,0.003738662,0.9927225,0.0001117996,0.0005312291,0.000009171128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9412162,0.001379013,0.05523253,0.0002842776,0.00002841653,0.00004976908,0.0002140469,0.0002627326,0.00133304],"genre_scores_gemma":[0.9674643,0.001743417,0.02947377,0.000074401,0.00001005403,0.00003089654,0.0002477563,0.00005192616,0.0009035059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007640087,"threshold_uncertainty_score":0.002555847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01020182598018132,"score_gpt":0.2521784077311489,"score_spread":0.2419765817509675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}