{"id":"W1964982955","doi":"10.4161/pri.2.1.6280","title":"Susceptibility of cell substrates to PrP<sup>Sc</sup>infection and safety control measures related to biological and biotherapeutical products","year":2008,"lang":"en","type":"review","venue":"Prion","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Food Inspection Agency; University of Ottawa; Health Canada","funders":"","keywords":"Infectious agent; Asymptomatic; Prion Proteins; Prion protein; Virology; Biology; Disease; Transmission (telecommunications); Medicine; Immunology; Pathology; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003444673,0.0003095414,0.0006781647,0.00007292696,0.00008473199,0.00001582768,0.0001029982,0.0004562313,0.00001253837],"category_scores_gemma":[0.0002687955,0.0002379715,0.0001536265,0.0001673285,0.0001072281,0.000003883776,0.0001018652,0.0001513631,0.000006114385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000255648,"about_ca_system_score_gemma":0.0001155803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001385188,"about_ca_topic_score_gemma":0.000006134803,"domain_scores_codex":[0.9981791,0.0002917249,0.0004715028,0.0007057624,0.0001156592,0.0002362225],"domain_scores_gemma":[0.9991919,0.0000426351,0.0001425065,0.0003198048,0.0001144154,0.0001887502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002905584,0.0001173079,0.001971785,0.001654668,0.0001184742,0.000001582761,0.00004271276,0.00001020665,0.02468061,0.00001235014,0.00008510465,0.9710146],"study_design_scores_gemma":[0.0006629021,0.001133004,0.004315379,0.0009252753,0.0002146512,0.00005958362,0.000007809252,0.00000994542,0.007295266,0.00003777631,0.9847706,0.0005677944],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.09935964,0.8988411,0.0001543335,0.0000633492,0.00003526323,0.001452292,0.00005630327,0.00001337968,0.00002435704],"genre_scores_gemma":[0.1146303,0.8848649,0.0002357154,0.00004007324,0.00006840191,0.00003954885,0.00008440964,0.00002104935,0.00001565469],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9846855,"threshold_uncertainty_score":0.9704195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02945752054293345,"score_gpt":0.2969085293746472,"score_spread":0.2674510088317138,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}