{"id":"W1965123277","doi":"10.1016/s0378-1119(99)00501-6","title":"Transcriptional regulation of the human DNA Methyltransferase (dnmt1) gene","year":2000,"lang":"en","type":"article","venue":"Gene","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Biology; DNMT1; DNA methylation; Enhancer; DNA methyltransferase; Gene; Epigenetics of physical exercise; Housekeeping gene; Genetics; Promoter; Regulation of gene expression; Epigenetics; CpG site; Regulatory sequence; Methyltransferase; Transcriptional regulation; Molecular biology; Methylation; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001232025,0.0001873823,0.0001363618,0.0001770866,0.0001702178,0.0002508209,0.0001448955,0.0001992582,0.001565836],"category_scores_gemma":[0.0002692821,0.0001092078,0.0001411086,0.00009920588,0.0002252352,0.0001502397,0.0002067502,0.0003251933,0.0004630569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005405072,"about_ca_system_score_gemma":0.0002027044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00144281,"about_ca_topic_score_gemma":0.002004738,"domain_scores_codex":[0.999915,0.00001680722,0.000002820904,0.000027069,0.000019803,0.00001840984],"domain_scores_gemma":[0.9999151,0.00002610126,0.00001919333,0.000009998163,0.00001519452,0.00001438647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001978264,0.00001259846,0.0008720464,0.00005606573,0.000006206641,0.00007043412,0.00003991432,0.0001898963,0.9906904,0.001227889,0.0002546343,0.006382091],"study_design_scores_gemma":[0.00001704347,0.00008328623,0.01764525,0.00001107722,0.00001198851,0.0002572114,0.00004202742,0.001355508,0.9751171,0.0004900225,0.004962891,0.000006472326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9723797,0.01011221,0.007777234,0.000790706,0.0001126338,0.00002093322,0.0009457548,0.0002441305,0.007616661],"genre_scores_gemma":[0.9911886,0.001332208,0.001262087,0.00006893343,0.00001320852,0.0000105442,0.0004304607,0.00002107586,0.005672858],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001565836,"threshold_uncertainty_score":0.005238295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01159324320054436,"score_gpt":0.2404486674789612,"score_spread":0.2288554242784168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}