{"id":"W1965214189","doi":"10.1016/j.bpj.2013.11.4090","title":"The Effect of Interhelical Loop Length and Composition on the Electrostatic Interactions of the Voltage Sensor Domain of JShak1","year":2014,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Helix (gastropod); Linker; Aspartic acid; Static electricity; Biophysics; Amino acid; Residue (chemistry); Potassium channel; Asparagine; Glutamic acid; Ion channel; Crystallography; Stereochemistry; Biochemistry; Biology; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004439574,0.0004021541,0.0002640215,0.000169446,0.0003744763,0.0005123924,0.0003993505,0.0003504453,0.002998844],"category_scores_gemma":[0.0009035867,0.000241859,0.0002378896,0.0001895762,0.0005182659,0.0005811404,0.0003440109,0.0008129904,0.0005131241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003777481,"about_ca_system_score_gemma":0.0002818618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005107744,"about_ca_topic_score_gemma":0.0006651189,"domain_scores_codex":[0.9997471,0.00007380669,0.00003483782,0.00004277498,0.00005320879,0.00004840707],"domain_scores_gemma":[0.9990968,0.0003839686,0.0001455938,0.00005059395,0.00008403149,0.0002391249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001684582,0.0001275048,0.0009729611,0.00004846428,0.00003132039,0.000101946,0.00006911662,0.0005504664,0.9945688,0.000169685,0.00007295347,0.001602188],"study_design_scores_gemma":[0.00008420109,0.0003728547,0.007118803,0.00001442846,0.00007052993,0.0001869503,0.00009291414,0.004561088,0.9861604,0.0001212544,0.001186138,0.00003038269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989543,0.0001946241,0.0003450437,0.00004222627,0.00001793761,0.00000569356,0.00006802005,0.00001043276,0.0003616395],"genre_scores_gemma":[0.9990119,0.00008078,0.000352549,0.00005210632,0.000008806058,0.000006371441,0.0001314818,0.00002185923,0.0003342275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002998844,"threshold_uncertainty_score":0.01003206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004873837092326858,"score_gpt":0.2349885368569765,"score_spread":0.2301146997646496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}