{"id":"W1965257810","doi":"10.1021/bm201037j","title":"Three-Dimensional Spatial Patterning of Proteins in Hydrogels","year":2011,"lang":"en","type":"article","venue":"Biomacromolecules","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Agarose; Self-healing hydrogels; Chemistry; Human serum albumin; Fusion protein; Maleimide; Biophysics; Serum albumin; Combinatorial chemistry; Biochemistry; Polymer chemistry; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001133946,0.0002323146,0.0001181626,0.0001078125,0.0001112749,0.0003124629,0.0002481059,0.0002165472,0.0004885584],"category_scores_gemma":[0.0001399946,0.0001873312,0.0001813009,0.0001018361,0.0002070231,0.0002400006,0.0002695822,0.0002824468,0.0002721782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002973146,"about_ca_system_score_gemma":0.0001523357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003193506,"about_ca_topic_score_gemma":0.0007081274,"domain_scores_codex":[0.9999146,0.000009988579,0.000006718831,0.00001817225,0.00003153766,0.0000188719],"domain_scores_gemma":[0.999918,0.00001943629,0.00002508059,0.000009607421,0.0000108238,0.00001712574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000110666,0.000005571887,0.0000427857,0.00001833782,0.000001876708,0.00002286636,0.00001246512,0.0004784104,0.9982581,0.0002272036,0.00003387512,0.0008874681],"study_design_scores_gemma":[0.000005520501,0.00002240223,0.000258529,0.000002333901,0.000002330378,0.00004230481,0.000008845864,0.002495104,0.9955794,0.00008351498,0.001494415,0.000005069124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9605742,0.0009424487,0.03418652,0.0001843077,0.00005334166,0.00004370592,0.0002835399,0.0002631399,0.003468763],"genre_scores_gemma":[0.9721299,0.0007157034,0.02419084,0.00008938408,0.00001132177,0.00006969569,0.0001726509,0.00004040534,0.002580096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004885584,"threshold_uncertainty_score":0.002157152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01588984427302673,"score_gpt":0.2536243717032388,"score_spread":0.2377345274302121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}