{"id":"W1965300511","doi":"10.1097/jcp.0b013e3181f1d10a","title":"Improving Fragile X-Associated Tremor/Ataxia Syndrome Symptoms With Memantine and Venlafaxine","year":2010,"lang":"en","type":"letter","venue":"Journal of Clinical Psychopharmacology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Research Resources; National Institute of Dental and Craniofacial Research; National Institute on Aging","keywords":"Venlafaxine; Ataxia; Memantine; Medicine; Psychiatry; Psychology; Internal medicine; Anxiety; NMDA receptor; Antidepressant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0007680588,0.000418464,0.0009956532,0.0001475202,0.00007793684,0.00003403265,0.0004968453,0.002017684,0.0001338532],"category_scores_gemma":[0.0002745104,0.0003318707,0.00031267,0.0001091086,0.0003386155,0.000006789033,0.0001508875,0.004236545,0.000007196486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000102913,"about_ca_system_score_gemma":0.0002873272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004204238,"about_ca_topic_score_gemma":0.00001142754,"domain_scores_codex":[0.9969207,0.0002844102,0.001430647,0.0005819899,0.0003302969,0.0004519799],"domain_scores_gemma":[0.9972683,0.0001600192,0.00178257,0.0002840267,0.0002877634,0.0002173367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001438683,0.0004178435,0.004326981,0.0001140043,0.001347245,0.001669744,0.00001384809,0.000006705996,0.1079631,2.534626e-7,0.8756645,0.007037098],"study_design_scores_gemma":[0.01101536,0.005971905,0.04052295,0.00009189932,0.000593516,0.002041293,0.000007250002,0.00002388377,0.00110556,0.00003946857,0.9379064,0.0006805391],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9396369,0.0009655174,0.00004457669,0.0556378,0.003264963,0.0002402326,0.00003767963,0.000007406121,0.0001649313],"genre_scores_gemma":[0.6219927,0.00248185,0.0009506677,0.3695827,0.002731852,0.00001317635,0.0001977915,0.0001707058,0.001878612],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3176442,"threshold_uncertainty_score":0.9999133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01410792342394423,"score_gpt":0.3230466045609727,"score_spread":0.3089386811370284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}