{"id":"W1965379686","doi":"10.1002/1096-8628(20001204)96:6<854::aid-ajmg32>3.0.co;2-n","title":"Detection of expansion regions in Portuguese bipolar families","year":2000,"lang":"en","type":"article","venue":"American Journal of Medical Genetics","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"National Institute of Mental Health","keywords":"Proband; Anticipation (artificial intelligence); Locus (genetics); Genetics; Trinucleotide repeat expansion; Population; Cohort; Biology; Disease; Demography; Internal medicine; Medicine; Allele; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002828519,0.00009044499,0.0003599671,0.0001809303,0.0000151128,0.000001879526,0.0000990981,0.00006615774,0.0002419938],"category_scores_gemma":[0.0000843823,0.00006722729,0.0001124684,0.0003422071,0.0002798809,0.00002142315,0.0000119801,0.0002825258,0.000004664581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003288602,"about_ca_system_score_gemma":0.000200234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002170025,"about_ca_topic_score_gemma":0.0001512363,"domain_scores_codex":[0.9984523,0.00007474757,0.0004939628,0.00008738117,0.0007470336,0.0001445645],"domain_scores_gemma":[0.9992867,0.000051626,0.0001805081,0.0001469659,0.00007768565,0.0002565352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0001897215,0.0003865431,0.03408341,0.00001255166,0.0000566825,0.00007241669,0.000411244,0.00001184258,0.001290213,0.000004264475,0.00002086672,0.9634603],"study_design_scores_gemma":[0.004132655,0.007108044,0.9424565,0.0005118218,0.0003054313,0.001875566,0.002576662,0.0004513708,0.008603013,0.000148239,0.03165772,0.0001729603],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796118,0.018354,0.0005913868,0.00107783,0.00006643607,0.00006746801,0.000001436438,0.000004894923,0.0002247308],"genre_scores_gemma":[0.9483069,0.05063725,0.0007660611,0.0001528813,0.00008415082,0.000001082114,0.000001483099,0.0000109482,0.00003924721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9632873,"threshold_uncertainty_score":0.2741449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01103997985675137,"score_gpt":0.2748321865213148,"score_spread":0.2637922066645634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}