{"id":"W1965392338","doi":"10.1073/pnas.1310755111","title":"Pch2 is a hexameric ring ATPase that remodels the chromosome axis protein Hop1","year":2013,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Synaptonemal complex; Homologous chromosome; Biology; Cell biology; Meiosis; Homologous recombination; DNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007446896,0.0001039904,0.0001040039,0.00005095203,0.000186225,0.00003528296,0.0009475864,0.00009049315,0.00002798987],"category_scores_gemma":[0.0002390421,0.00005938901,0.00008700377,0.0003266893,0.000585132,0.00004451059,0.0002935763,0.0001083175,0.000004704339],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001410685,"about_ca_system_score_gemma":0.00003346581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001665448,"about_ca_topic_score_gemma":4.937862e-8,"domain_scores_codex":[0.9985736,0.000008397093,0.0001970112,0.0002847357,0.0007605139,0.0001757344],"domain_scores_gemma":[0.9994211,0.000016777,0.0003019845,0.00002140467,0.0002054826,0.00003329062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000004516667,0.00001730637,0.0002776229,0.00002212401,0.00001258677,1.95315e-9,0.00007396528,0.0000130179,0.9954576,0.003037806,0.0006125237,0.0004708839],"study_design_scores_gemma":[0.00009289527,0.00006546836,0.002441956,0.00004206368,0.000005340936,0.000007696055,0.0001333791,0.0008860409,0.9755071,0.02031119,0.0004278071,0.00007905945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922718,0.0001736816,0.000004992088,0.004008634,0.00001306695,0.0004061123,0.000006921912,0.000007636004,0.003107153],"genre_scores_gemma":[0.9966863,0.00002507197,0.001707505,0.0006867926,0.0000814522,0.0000592145,1.697841e-7,0.000006342626,0.00074713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01995054,"threshold_uncertainty_score":0.2421813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03175063911583484,"score_gpt":0.2719749403380909,"score_spread":0.240224301222256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}