{"id":"W1965466808","doi":"10.1016/j.molcel.2005.05.012","title":"Binding of pRB to the PHD Protein RBP2 Promotes Cellular Differentiation","year":2005,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":242,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Biology; E2F; Transcription factor; Cell biology; Retinoblastoma protein; Chromatin; Pioneer factor; Forkhead Transcription Factors; Chromatin immunoprecipitation; Promoter; Genetics; Chromatin remodeling; Gene; Gene expression; Cell cycle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001951351,0.0003150796,0.0003449056,0.0002804432,0.0003237539,0.0005932943,0.0002286806,0.0002549972,0.002661653],"category_scores_gemma":[0.0001968856,0.0002895137,0.0002904404,0.000188155,0.0002736877,0.0002141898,0.0003126486,0.0009870633,0.001152608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006446556,"about_ca_system_score_gemma":0.0003478912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001354208,"about_ca_topic_score_gemma":0.002712953,"domain_scores_codex":[0.999786,0.00002545104,0.000012413,0.00003791445,0.00006284713,0.00007549687],"domain_scores_gemma":[0.9998139,0.00004181036,0.00002559602,0.00002980786,0.0000195561,0.00006936479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001977738,0.00002537716,0.0001009802,0.00003558572,0.000004572681,0.0000397318,0.000009354764,0.00005627609,0.9978712,0.0001721313,0.0001749515,0.001312124],"study_design_scores_gemma":[0.00001902051,0.00007036412,0.001954237,0.000002193106,0.000004178328,0.0001000268,0.00001450692,0.0004706596,0.99246,0.00004122717,0.004861099,0.000002503657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9666078,0.0123427,0.009541931,0.000607277,0.000195833,0.00005007616,0.0007289459,0.0005322899,0.009393075],"genre_scores_gemma":[0.9826147,0.001918049,0.002866818,0.00009802914,0.00003918498,0.00002600669,0.000823094,0.00007847515,0.01153562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002661653,"threshold_uncertainty_score":0.008904099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007227782632790802,"score_gpt":0.2050898648381059,"score_spread":0.1978620822053151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}