{"id":"W1965485439","doi":"10.1080/13880200600746196","title":"The Inhibition of Human Cytochrome P450 by Ethanol Extracts of North American Botanicals","year":2006,"lang":"en","type":"article","venue":"Pharmaceutical Biology","topic":"Medicinal Plants and Bioactive Compounds","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; University of Ottawa","funders":"Health Canada","keywords":"Phytochemical; Biology; Achillea millefolium; Botany; CYP3A4; Traditional medicine; Cytochrome P450; Metabolism; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002120742,0.0001252913,0.0002236821,0.00001999513,0.00007495064,0.000004025115,0.0001573182,0.0000716245,0.0000174399],"category_scores_gemma":[0.00006229826,0.00008171253,0.00007536235,0.0001013994,0.001008998,0.000001997129,0.0000777411,0.0001327268,0.000002593919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008853202,"about_ca_system_score_gemma":0.00002478676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008313572,"about_ca_topic_score_gemma":0.00007025341,"domain_scores_codex":[0.9989237,0.0001431558,0.0003499254,0.0002323989,0.00009705203,0.0002538283],"domain_scores_gemma":[0.9993661,0.0001008901,0.000197549,0.0001777446,0.00008762896,0.00007009785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001474543,0.0001124245,0.008284535,0.00001093522,0.00003960729,0.000001302173,0.000001843446,4.15697e-7,0.9835417,0.0003354579,0.001773619,0.005750727],"study_design_scores_gemma":[0.0004334258,0.0006929382,0.04011596,0.00000586201,0.00002857215,0.000008918397,0.00000797645,0.00001007117,0.9139149,0.0001212829,0.04455077,0.0001093658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973142,0.000720356,0.0002702391,0.0004725904,0.00004277049,0.0001349441,0.0001138324,0.00000581241,0.0009252667],"genre_scores_gemma":[0.9987966,0.0003526859,0.00003566219,0.000229141,0.0002017055,0.000009015771,0.000308204,0.000008392733,0.00005861902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06962682,"threshold_uncertainty_score":0.3717696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02286628896215817,"score_gpt":0.3428906377519854,"score_spread":0.3200243487898273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}