{"id":"W1965527358","doi":"10.1016/s0169-5002(01)00397-x","title":"Potential of 5-aza-2′-deoxycytidine (Decitabine) a potent inhibitor of DNA methylation for therapy of advanced non-small cell lung cancer","year":2001,"lang":"en","type":"article","venue":"Lung Cancer","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Notre-Dame; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Decitabine; Epigenetics; DNA methylation; Lung cancer; Medicine; Carcinogenesis; Deoxycytidine; Cancer research; Methylation; Epigenetic therapy; Cancer; Oncology; Gene; Biology; Internal medicine; Gene expression; Genetics; Gemcitabine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002447188,0.0002541845,0.00068021,0.0002425314,0.0001946653,0.0003215368,0.0003368969,0.0002836945,0.001599728],"category_scores_gemma":[0.0001415692,0.0001181812,0.0001718235,0.0002016193,0.0001488794,0.0001281142,0.0001439525,0.0006696488,0.0003472216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004213555,"about_ca_system_score_gemma":0.0003855562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001877709,"about_ca_topic_score_gemma":0.005262841,"domain_scores_codex":[0.9999328,0.00002182591,0.00000432601,0.00001019339,0.000009134045,0.00002169153],"domain_scores_gemma":[0.9999558,0.00001391986,0.00000553663,0.000006083739,0.000006848219,0.00001198974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003883395,0.0004829885,0.0007963551,0.0003825063,0.00007377218,0.0004432709,0.00008946564,0.001380202,0.8906045,0.002591834,0.001177749,0.09809398],"study_design_scores_gemma":[0.001231344,0.008029193,0.007484858,0.00004132585,0.0002464381,0.001491623,0.00005302293,0.00247798,0.9206008,0.0003800418,0.05794281,0.00002041329],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8856943,0.08911331,0.005931928,0.0009842068,0.0003116074,0.0002994291,0.0008123398,0.0002110028,0.01664194],"genre_scores_gemma":[0.9706236,0.02086351,0.001609194,0.0001550419,0.00005914822,0.00008079739,0.0004305881,0.00002313555,0.006155048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001877709,"threshold_uncertainty_score":0.005351603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008718673126525666,"score_gpt":0.2836352383365898,"score_spread":0.2749165652100641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}