{"id":"W1965531365","doi":"10.1016/j.ccr.2006.07.016","title":"pVHL's kryptonite: E2-EPF UCP","year":2006,"lang":"en","type":"review","venue":"Cancer Cell","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Ubiquitin; Proteasome; Protein subunit; Carcinogenesis; Deubiquitinating enzyme; Biology; Suppressor; Hypoxia-inducible factors; Ubiquitin ligase; Cell biology; Cancer research; Cancer; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001064068,0.0005811692,0.001101549,0.00005728515,0.00008283926,0.00004665962,0.0004882066,0.000678809,0.0003232078],"category_scores_gemma":[0.00000892501,0.000523145,0.000727975,0.0001608938,0.00009017234,0.000003676592,0.0001639576,0.0002745138,0.000098422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001114528,"about_ca_system_score_gemma":0.0008330294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003821641,"about_ca_topic_score_gemma":0.0002748763,"domain_scores_codex":[0.9979264,0.00008262166,0.000477557,0.0008017102,0.0001861393,0.00052555],"domain_scores_gemma":[0.998606,0.00001200681,0.0003236928,0.0008061274,0.00008973187,0.0001624318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007393105,0.00004574699,0.000001320102,0.004065871,0.000095577,0.000002320118,0.000006630778,0.000003810074,0.0006207766,0.00001518873,0.1795104,0.815625],"study_design_scores_gemma":[0.0003068201,0.00003973328,0.000001539987,0.000690437,0.0005897178,0.0000119545,0.000004329601,3.377076e-7,0.00101104,0.000006810942,0.9967197,0.00061759],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000148881,0.9705083,0.00006023805,0.000007448876,0.004093411,0.0005156329,0.0003977421,0.00002622427,0.02437612],"genre_scores_gemma":[0.000004539646,0.9571549,0.0001240414,0.0002021871,0.009970311,0.000350884,0.001052607,0.0001331355,0.0310074],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8172093,"threshold_uncertainty_score":0.999722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02240858975732659,"score_gpt":0.3128650307853649,"score_spread":0.2904564410280383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}