{"id":"W1965593580","doi":"10.1002/smll.201102413","title":"Self‐Assembling Peptide‐Based Nanoparticles for siRNA Delivery in Primary Cell Lines","year":2012,"lang":"en","type":"article","venue":"Small","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Agence Nationale de la Recherche; McMaster University","keywords":"Peptide; Nanoparticle; Small interfering RNA; Amphiphile; RNA interference; Nanotechnology; Biophysics; Materials science; RNA; Chemistry; Biochemistry; Biology; Copolymer; Organic chemistry; Polymer","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001946853,0.0001314275,0.0001205268,0.00005006473,0.00004015801,0.00001813964,0.0001456962,0.0001150556,0.000005646582],"category_scores_gemma":[0.00002506267,0.0001272078,0.00009124762,0.0000567515,0.00001752497,0.000007751472,0.00005536349,0.00005351522,0.00002046437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001845335,"about_ca_system_score_gemma":0.00007011905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001509169,"about_ca_topic_score_gemma":0.00005441013,"domain_scores_codex":[0.9991552,0.00002970177,0.0001909477,0.0002116901,0.00005708104,0.0003553869],"domain_scores_gemma":[0.9995753,0.00002690895,0.00005324643,0.0001990652,0.00006964837,0.00007589831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000112139,0.0001875116,0.01674695,0.00007285611,0.0000120079,0.000001075411,0.00006159339,0.000105175,0.9811561,0.000006539012,0.000693981,0.0008440532],"study_design_scores_gemma":[0.0006800646,0.0002128638,0.005350825,0.00001892183,0.00001789115,0.000001787851,0.00006653899,0.0003662025,0.9801351,0.00001138437,0.0129396,0.0001988187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964759,0.001739443,0.000505782,0.00005834036,0.0001786085,0.00019453,0.00001018841,0.00001741668,0.0008198204],"genre_scores_gemma":[0.9926654,0.0001092934,0.00575378,0.0006244911,0.0003595353,0.00004929487,0.00007881757,0.0000208807,0.0003385601],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01224562,"threshold_uncertainty_score":0.5187382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02339705807007592,"score_gpt":0.242994035868329,"score_spread":0.2195969777982531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}