{"id":"W1965650772","doi":"10.1089/10799900050023852","title":"Review: Molecular Mechanism of Ultraviolet-Induced Keratinocyte Apoptosis","year":2000,"lang":"en","type":"review","venue":"Journal of Interferon & Cytokine Research","topic":"Skin Protection and Aging","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"Medical Research Council Canada; Canadian Dermatology Foundation; Dermatology Foundation","keywords":"Fas ligand; Death domain; Apoptosis; FADD; Cell biology; Signal transduction; Tumor necrosis factor alpha; Caspase; Programmed cell death; Biology; Fas receptor; Keratinocyte; Caspase 8; Chemistry; Immunology; Cell culture; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004157462,0.0004747836,0.0035032,0.001659931,0.00008259046,0.00004376934,0.0006762807,0.0004038589,0.001230206],"category_scores_gemma":[0.001014765,0.0003279067,0.001526907,0.001146958,0.000105158,0.0001019198,0.0001406301,0.003896015,0.0001222259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000481871,"about_ca_system_score_gemma":0.001065479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002213826,"about_ca_topic_score_gemma":4.370729e-7,"domain_scores_codex":[0.9937156,0.001210425,0.002474857,0.0004001191,0.001623684,0.0005752602],"domain_scores_gemma":[0.9959199,0.0003229177,0.00117793,0.0006938136,0.001505692,0.0003796745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002819436,0.0002846615,2.717128e-7,0.05378674,0.0007516505,0.0002981624,0.00003305556,2.242567e-7,0.01152248,0.00008775852,0.007223934,0.9257291],"study_design_scores_gemma":[0.0007042387,0.002603342,2.267103e-7,0.3046577,0.0009230545,0.002717986,0.00003477894,0.000003210739,0.02622468,0.0000483959,0.6618631,0.000219297],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002426445,0.9952584,0.0001812351,0.0005737534,0.000266145,0.001373453,0.00001222246,0.00001564231,0.002076505],"genre_scores_gemma":[0.001085183,0.9972282,0.0003305386,0.0002459413,0.0004957826,0.00005156118,0.00001422875,0.0001022654,0.0004462824],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9255098,"threshold_uncertainty_score":0.9999173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1534602648221701,"score_gpt":0.4616892588746663,"score_spread":0.3082289940524962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}