{"id":"W1965774125","doi":"10.1242/jcs.119297","title":"Regulation of telomere length and homeostasis by telomerase enzyme processivity","year":2012,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Telomere; Processivity; Telomerase; Biology; Telomerase reverse transcriptase; Telomerase RNA component; Reverse transcriptase; Cell biology; Ribonucleoprotein; Molecular biology; RNA; DNA; DNA replication; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001662774,0.0001911721,0.0001734277,0.0002329046,0.000151836,0.0005142128,0.000205401,0.0002476986,0.0005703587],"category_scores_gemma":[0.0002140816,0.0001149417,0.0002189975,0.0001525772,0.0002028848,0.0003671152,0.0003015228,0.0003031115,0.0002071111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002580207,"about_ca_system_score_gemma":0.0001399581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002063398,"about_ca_topic_score_gemma":0.0001621893,"domain_scores_codex":[0.9998558,0.00001883596,0.00001502326,0.00004884813,0.00003605812,0.00002542824],"domain_scores_gemma":[0.9998178,0.00002343131,0.00006905939,0.00002740321,0.00002362746,0.00003884554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000824519,0.00000755986,0.0005854797,0.00001427238,0.000002608321,0.00003074604,0.00001855439,0.00007282172,0.9975484,0.0001460501,0.00001342873,0.00147775],"study_design_scores_gemma":[0.00002293069,0.0003011916,0.0291363,0.00001019094,0.00001848503,0.0005144736,0.00004733105,0.001485409,0.9649074,0.0004352333,0.003108865,0.00001215173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922919,0.003936189,0.002366149,0.00005704646,0.0000136716,0.000009508106,0.0002063179,0.00006107457,0.001058059],"genre_scores_gemma":[0.9970457,0.001044025,0.000941193,0.00001643824,0.000007675027,0.00001012949,0.0001873329,0.00001051955,0.0007368651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005703587,"threshold_uncertainty_score":0.001908004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01137411582464243,"score_gpt":0.2612757060705909,"score_spread":0.2499015902459485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}