{"id":"W1965807091","doi":"10.1016/j.vaccine.2012.01.087","title":"Comparison of safety and immunogenicity of two doses of investigational hepatitis B virus surface antigen co-administered with an immunostimulatory phosphorothioate oligodeoxyribonucleotide and three doses of a licensed hepatitis B vaccine in healthy adults 18–55 years of age","year":2012,"lang":"en","type":"article","venue":"Vaccine","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Alberta Health Services; McGill University Health Centre; University of Manitoba; Institut National de Santé Publique du Québec; Izaak Walton Killam Health Centre; Ottawa Hospital; Capital District Health Authority; Dalhousie University","funders":"","keywords":"Medicine; Immunogenicity; HBsAg; Hepatitis B virus; Hepatitis A vaccine; Hepatitis B; Tolerability; Immunology; Virology; Antibody; Internal medicine; Gastroenterology; Adverse effect; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001791156,0.0006990196,0.0008835731,0.0003953229,0.0002860459,0.0003998615,0.0004635018,0.001184182,0.0009314522],"category_scores_gemma":[0.002958561,0.0004413892,0.001009712,0.0003081741,0.0008694979,0.0008414717,0.0002515482,0.001026286,0.0002268313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003417828,"about_ca_system_score_gemma":0.0004151373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007758308,"about_ca_topic_score_gemma":0.0005720368,"domain_scores_codex":[0.9990942,0.0005014381,0.00007131438,0.0001265925,0.0001069863,0.00009944058],"domain_scores_gemma":[0.997728,0.001203172,0.0003274027,0.0002260448,0.0001939005,0.0003213991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8674686,0.02510089,0.03453374,0.0003050214,0.0008277627,0.0002610968,0.0005463246,0.0006163616,0.04728543,0.0001139738,0.0001086131,0.02283216],"study_design_scores_gemma":[0.02710907,0.908694,0.05014977,0.00001576814,0.0005589786,0.0001823228,0.0001274142,0.0003938534,0.01236899,0.00005831624,0.0003224479,0.00001915875],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995673,0.0001924299,0.00004894501,0.0000104795,0.00001461521,0.00002967643,0.00002164967,0.000001467427,0.0001134368],"genre_scores_gemma":[0.9993966,0.0001472287,0.00007250731,0.0000313044,0.00005391138,0.00003499573,0.00007991122,0.000001826367,0.0001816934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001791156,"threshold_uncertainty_score":0.009472609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03313659571203852,"score_gpt":0.3264030798311917,"score_spread":0.2932664841191532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}