{"id":"W1965847849","doi":"10.1016/s0006-291x(02)02187-3","title":"Calpain is required for MMP-2 and u-PA expression in SV40 large T-antigen-immortalized cells","year":2002,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Calpain; Antigen; Matrix metalloproteinase; Molecular biology; Cell biology; Chemistry; Biology; Enzyme; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004747021,0.0001221708,0.0001462979,0.00007640383,0.0002888358,0.00004414093,0.0002585318,0.0001988197,0.00002923714],"category_scores_gemma":[0.0002666757,0.0001041348,0.00006998477,0.0002126732,0.0004332646,0.000008906753,0.0003923023,0.0002024739,0.000008184942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001676141,"about_ca_system_score_gemma":0.00002035965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001828723,"about_ca_topic_score_gemma":0.00001060198,"domain_scores_codex":[0.9986895,0.0001999323,0.0002175769,0.0003738247,0.000197222,0.0003219334],"domain_scores_gemma":[0.9988569,0.0001468197,0.00003778873,0.0006520858,0.00013906,0.0001673254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008444706,0.0003145383,0.0001597514,0.00002918056,0.00001008612,2.536611e-7,0.00007018827,8.391347e-8,0.9855509,0.0004656281,0.011609,0.001705915],"study_design_scores_gemma":[0.001268465,0.0001917023,0.001115391,0.00005517499,0.000006682102,0.00000188963,0.0001141456,0.00567531,0.8583352,0.0006961268,0.1323379,0.0002020586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904091,0.003474172,0.0008030796,0.004025334,0.00002890226,0.0007645173,0.0001031208,0.00001818639,0.0003735622],"genre_scores_gemma":[0.993714,0.003075244,0.001607259,0.0001852267,0.00009988054,0.0001818902,0.0001826712,0.00001484192,0.0009389458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1272157,"threshold_uncertainty_score":0.4246493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0759527540141884,"score_gpt":0.3610807509055225,"score_spread":0.2851279968913341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}