{"id":"W1965847849","doi":"10.1016/s0006-291x(02)02187-3","title":"Calpain is required for MMP-2 and u-PA expression in SV40 large T-antigen-immortalized cells","year":2002,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Calpain; Antigen; Matrix metalloproteinase; Molecular biology; Cell biology; Chemistry; Biology; Enzyme; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003137779,0.0004911263,0.0006049426,0.0008249502,0.0004589706,0.001047914,0.0004812431,0.0005096316,0.001537898],"category_scores_gemma":[0.0005633869,0.0004173024,0.0006256081,0.0004670397,0.0004066766,0.0006527186,0.0004544223,0.00118047,0.001087829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006704509,"about_ca_system_score_gemma":0.0003787825,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001357685,"about_ca_topic_score_gemma":0.00108058,"domain_scores_codex":[0.9995384,0.00005813643,0.0000761333,0.00006377868,0.0001322752,0.0001312343],"domain_scores_gemma":[0.9988674,0.0003539737,0.0001968441,0.0002479161,0.0001429406,0.0001909924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000105936,0.00002656232,0.0001451821,0.00001061578,0.000003382854,0.00009285141,0.00002269693,0.00001607168,0.9991311,0.0001293481,0.00002210603,0.0002942869],"study_design_scores_gemma":[0.00001127944,0.0000490693,0.00346839,0.000002314412,0.000008173032,0.0004903578,0.00003445776,0.0005161007,0.9942257,0.00007074441,0.001119512,0.000004021555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900768,0.001514322,0.0057744,0.0001739428,0.00006650712,0.00003486883,0.001043783,0.0002775055,0.001037969],"genre_scores_gemma":[0.9895607,0.0005173682,0.003204894,0.00005228062,0.00003926882,0.00005439716,0.002820767,0.00008808806,0.003662246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001537898,"threshold_uncertainty_score":0.005144775,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0759527540141884,"score_gpt":0.3610807509055225,"score_spread":0.2851279968913341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}