{"id":"W1965894562","doi":"10.1016/s0002-9440(10)64960-7","title":"Endoglin Expression Is Reduced in Normal Vessels but Still Detectable in Arteriovenous Malformations of Patients with Hereditary Hemorrhagic Telangiectasia Type 1","year":2000,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Vascular Anomalies and Treatments","field":"Medicine","cited_by":126,"is_retracted":false,"has_abstract":false,"ca_institutions":"North York General Hospital; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute; Medical Research Council; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Endoglin; Immunostaining; Medicine; Pathology; Telangiectasia; Arteriovenous malformation; Missense mutation; Intracardiac injection; Blood vessel; Densitometry; Molecular biology; Immunohistochemistry; Mutation; Chemistry; Internal medicine; Radiology; Biology; CD34; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001054848,0.0002607116,0.0003183141,0.0009417834,0.0002318223,0.000324391,0.0001557472,0.0003619515,0.00214149],"category_scores_gemma":[0.000839838,0.0001589249,0.000154366,0.0004297344,0.0002740128,0.0001790271,0.0001599684,0.0002385283,0.0001455974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001201901,"about_ca_system_score_gemma":0.00007196813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005839599,"about_ca_topic_score_gemma":0.000431925,"domain_scores_codex":[0.9998333,0.00002405247,0.00001922455,0.00004778007,0.00004373066,0.00003185028],"domain_scores_gemma":[0.9996631,0.0001174026,0.0001185172,0.00001712667,0.00002742634,0.00005641108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001787401,0.000105987,0.3315407,0.00009293245,0.0001366568,0.01691002,0.0006950916,0.0001763682,0.6296857,0.0002270324,0.000464075,0.01817803],"study_design_scores_gemma":[0.00003055895,0.0001828126,0.95377,0.000005499144,0.0001067572,0.02499756,0.000210464,0.0003975053,0.0196447,0.0001248913,0.0005208497,0.000008287448],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993256,0.000140482,0.0001505925,0.00001640966,0.000003068835,0.000001274881,0.00006585595,0.000007991542,0.0002886282],"genre_scores_gemma":[0.9995044,0.00006367611,0.0001248886,0.00001169394,0.000007223136,0.000002524203,0.00008107899,0.000004897146,0.0001994877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00214149,"threshold_uncertainty_score":0.007163942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005063607425173195,"score_gpt":0.220644171705217,"score_spread":0.2155805642800438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}