{"id":"W1965902126","doi":"10.1074/jbc.m112.403386","title":"Crystal Structures of a CTXφ pIII Domain Unbound and in Complex with a Vibrio cholerae TolA Domain Reveal Novel Interaction Interfaces","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"SLAC National Accelerator Laboratory; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Office of Science; Howard Hughes Medical Institute; Norges Forskningsråd; U.S. Department of Energy; Universitetet i Oslo; Michael Smith Health Research BC","keywords":"Vibrio cholerae; Cholera toxin; Periplasmic space; Colicin; Pilus; Filamentous bacteriophage; Biology; Prophage; Bacteriophage; Microbiology; Cell biology; Escherichia coli; Genetics; Gene; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001300963,0.0005891639,0.0004148512,0.0001669755,0.0006237984,0.0007884492,0.0007755595,0.0005450021,0.001386843],"category_scores_gemma":[0.0002581078,0.0003482277,0.0002534781,0.0003517589,0.0004246514,0.000356324,0.0002986333,0.001855458,0.0002367418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0016,"about_ca_system_score_gemma":0.0007546167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009150083,"about_ca_topic_score_gemma":0.006368517,"domain_scores_codex":[0.9998479,0.000008462212,0.000005282842,0.00003034264,0.00006817783,0.00003980648],"domain_scores_gemma":[0.9998907,0.00002337158,0.00002092629,0.000005102635,0.00001444025,0.00004543321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001458838,0.0008505791,0.01437711,0.0004200294,0.000191963,0.002404515,0.0007643256,0.006005002,0.9615154,0.002173749,0.003232706,0.006605801],"study_design_scores_gemma":[0.0008708481,0.0009018519,0.2217747,0.00013362,0.0003096854,0.005480404,0.001779732,0.08996814,0.6481691,0.001315948,0.02910472,0.0001911032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955154,0.001301845,0.0008314252,0.0002270548,0.00003312568,0.00001433134,0.000345729,0.00006925937,0.001661911],"genre_scores_gemma":[0.9917948,0.0009928392,0.00157215,0.0001443494,0.00001486143,0.0000218912,0.002446815,0.0000277464,0.002984651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009150083,"threshold_uncertainty_score":0.01819366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0194182691500825,"score_gpt":0.2566912551716969,"score_spread":0.2372729860216145,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}