{"id":"W1965958209","doi":"10.1002/pros.21356","title":"Antiandrogenic and growth inhibitory effects of ring‐substituted analogs of 3,3′‐diindolylmethane (Ring‐DIMs) in hormone‐responsive LNCaP human prostate cancer cells","year":2011,"lang":"en","type":"article","venue":"The Prostate","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Texas A and M University; Natural Sciences and Engineering Research Council of Canada; Texas AgriLife Research","keywords":"LNCaP; Transfection; Androgen receptor; Prostate cancer; Biology; Endocrinology; Androgen; Internal medicine; Cancer research; Chemistry; Molecular biology; Cell culture; Medicine; Cancer; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002377094,0.0002103735,0.0003073977,0.00008922353,0.0000507458,0.000006665889,0.0002127242,0.0001014946,0.000004066223],"category_scores_gemma":[0.0000553791,0.000170995,0.00007576817,0.0001317911,0.0004461852,0.000008798395,0.0001932004,0.0001419851,0.000001082536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001302745,"about_ca_system_score_gemma":0.00006489608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004705392,"about_ca_topic_score_gemma":0.0001287891,"domain_scores_codex":[0.9987848,0.0001240404,0.0003460188,0.0003418106,0.0001062573,0.0002970833],"domain_scores_gemma":[0.9991968,0.00003312868,0.0002667043,0.0002988828,0.0001348032,0.00006971516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006870971,0.00009401457,0.01136375,0.0001881487,0.00009795298,0.000007154491,0.002117987,0.00001066394,0.9851399,0.00006953158,0.0000279194,0.0001958753],"study_design_scores_gemma":[0.001482635,0.0002492657,0.0630606,0.00008224852,0.0000450671,0.000002823259,0.0001095012,0.000005287086,0.9341897,0.0005724666,0.00002157366,0.0001788729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945032,0.004504865,0.00001356001,0.00001452711,0.00007349481,0.0006385464,0.00007379727,0.0000063506,0.0001716654],"genre_scores_gemma":[0.9978436,0.001783119,0.000124495,0.00003149297,0.00003619266,0.00005865676,0.00002646445,0.0000254027,0.00007057415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05169685,"threshold_uncertainty_score":0.6972973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009122782269801361,"score_gpt":0.229052666185196,"score_spread":0.2199298839153946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}