{"id":"W1965958209","doi":"10.1002/pros.21356","title":"Antiandrogenic and growth inhibitory effects of ring‐substituted analogs of 3,3′‐diindolylmethane (Ring‐DIMs) in hormone‐responsive LNCaP human prostate cancer cells","year":2011,"lang":"en","type":"article","venue":"The Prostate","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Texas A and M University; Natural Sciences and Engineering Research Council of Canada; Texas AgriLife Research","keywords":"LNCaP; Transfection; Androgen receptor; Prostate cancer; Biology; Endocrinology; Androgen; Internal medicine; Cancer research; Chemistry; Molecular biology; Cell culture; Medicine; Cancer; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008366086,0.0001946431,0.0001136083,0.0001224097,0.00007755985,0.00008331248,0.0001742718,0.0001209811,0.001350255],"category_scores_gemma":[0.00005425842,0.00008221656,0.0001575934,0.0001178702,0.0001032443,0.00006882756,0.00005224843,0.0002516072,0.0002818032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001591069,"about_ca_system_score_gemma":0.0001455121,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004921542,"about_ca_topic_score_gemma":0.0009122746,"domain_scores_codex":[0.9999566,0.000008226041,0.000003802194,0.00000952995,0.00001232142,0.000009510312],"domain_scores_gemma":[0.9999444,0.00001395114,0.00001421223,0.000006755951,0.000006397034,0.00001424474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001304579,0.00002803907,0.00007735119,0.00004181823,0.000003717881,0.00001570679,0.000008429428,0.00007074998,0.9985744,0.00001791991,0.00004072061,0.0009906804],"study_design_scores_gemma":[0.00001878509,0.0007550682,0.002305772,0.000002508558,0.00001083059,0.0001178531,0.00001140219,0.0002532596,0.9949443,0.000008444548,0.001568942,0.000002903312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993633,0.003018871,0.0006566732,0.00006168883,0.00002270581,0.00002170348,0.0006193054,0.00006470824,0.001901257],"genre_scores_gemma":[0.9944581,0.001414734,0.001173052,0.00004216377,0.00001065041,0.00002513669,0.0008613517,0.00001267553,0.002002167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001350255,"threshold_uncertainty_score":0.004517078,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009122782269801361,"score_gpt":0.229052666185196,"score_spread":0.2199298839153946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}