{"id":"W1965975821","doi":"10.1016/j.cell.2008.06.018","title":"Acetylation of Histone H3 Lysine 56 Regulates Replication-Coupled Nucleosome Assembly","year":2008,"lang":"en","type":"article","venue":"Cell","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":443,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Histone octamer; Nucleosome; Biology; Histone code; Histone; Histone H3; Histone methylation; Histone H2A; Cell biology; Chromatin; Histone H1; DNA replication; DNA; Genetics; DNA methylation; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007658091,0.00008944429,0.000114789,0.00002540406,0.00005788086,0.000003991248,0.0001310116,0.0001007914,0.00001993899],"category_scores_gemma":[0.00002337395,0.00009395119,0.00008073941,0.00006482582,0.00005635387,0.000002322564,0.00004896562,0.00003364283,0.00001285562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001565855,"about_ca_system_score_gemma":0.00004209461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001617859,"about_ca_topic_score_gemma":0.000004733432,"domain_scores_codex":[0.9993554,0.00001214205,0.0002071136,0.0002420008,0.00007390783,0.0001094345],"domain_scores_gemma":[0.9991525,0.000005741867,0.0001518027,0.0005590495,0.00009392104,0.00003701063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001352919,0.00005932464,0.0004194179,0.00001748815,0.00001335407,5.744149e-7,0.00004736583,0.0003095386,0.9980586,0.00003514961,0.0009318413,0.0000938214],"study_design_scores_gemma":[0.0004181048,0.0001008977,0.01007021,0.000004416022,0.00001734345,0.00001044049,0.00001791403,0.005289423,0.9796298,0.00008272062,0.004218218,0.0001405262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968396,0.0004864383,0.0006829521,0.00007941588,0.00005451862,0.00009668682,0.000007317552,0.000009526451,0.001743536],"genre_scores_gemma":[0.9941255,0.0002913762,0.002093944,0.00004410115,0.00008305795,0.000005457742,0.0002648127,0.00001887261,0.00307287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01842881,"threshold_uncertainty_score":0.3831218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007569700904310122,"score_gpt":0.2361805487479303,"score_spread":0.2286108478436202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}