{"id":"W1966014719","doi":"10.1016/j.bbr.2015.04.012","title":"Early detection of cognitive deficits in the 3xTg-AD mouse model of Alzheimer's disease","year":2015,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":219,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Fear conditioning; Psychology; Cued speech; Barnes maze; Neuroscience; Cognition; Audiology; Hippocampus; Effects of sleep deprivation on cognitive performance; Medicine; Cognitive psychology; Spatial learning; Amygdala","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004993679,0.001513288,0.0008305206,0.002900833,0.0004900544,0.001015204,0.0006702336,0.001617672,0.001851212],"category_scores_gemma":[0.000356642,0.0005994444,0.001146544,0.0006060896,0.0008568591,0.0008941338,0.0005526245,0.0030008,0.0005951049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007586451,"about_ca_system_score_gemma":0.0004825102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002543358,"about_ca_topic_score_gemma":0.003985901,"domain_scores_codex":[0.9996126,0.00003944954,0.00004634672,0.00009147834,0.0001123337,0.00009774094],"domain_scores_gemma":[0.9992703,0.00006598463,0.0002599705,0.00006032853,0.0001298739,0.0002136812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009660707,0.0003119417,0.001013525,0.00007599568,0.00003658103,0.0004231554,0.00009570834,0.00005411989,0.9946544,0.0002089852,0.0002243265,0.001935069],"study_design_scores_gemma":[0.0001878292,0.002074415,0.04165466,0.00008229662,0.0002431711,0.002426085,0.0002548384,0.001329624,0.9475873,0.00090096,0.00319449,0.00006441917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862404,0.002910669,0.005268126,0.0005632672,0.000165933,0.0001057557,0.002092819,0.0005337638,0.002119208],"genre_scores_gemma":[0.9762717,0.003171851,0.006437969,0.0003654835,0.00005208281,0.0002520104,0.001828089,0.0001814708,0.01143928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002900833,"threshold_uncertainty_score":0.006192863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2238795598170864,"score_gpt":0.415068758269808,"score_spread":0.1911891984527216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}