{"id":"W1966040155","doi":"10.1007/s10637-007-9044-9","title":"Phase II study of Triapine® in patients with metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC IND.161)","year":2007,"lang":"en","type":"article","venue":"Investigational New Drugs","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University; London Health Sciences Centre; Princess Margaret Cancer Centre; BC Cancer Agency; Juravinski Cancer Centre; Hamilton Health Sciences; University Health Network","funders":"","keywords":"Medicine; Renal cell carcinoma; Nausea; Adverse effect; Internal medicine; Neutropenia; Urology; Vomiting; Clinical trial; Gastroenterology; Oncology; Surgery; Toxicity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001180169,0.00145762,0.001849557,0.0003829045,0.0005316746,0.0009048988,0.00081299,0.001200892,0.005084876],"category_scores_gemma":[0.001038557,0.0003498142,0.001657178,0.0004705498,0.0006767842,0.0005953123,0.0003037329,0.003062767,0.0008014441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001693101,"about_ca_system_score_gemma":0.003708234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01097686,"about_ca_topic_score_gemma":0.02711598,"domain_scores_codex":[0.9997041,0.0001459385,0.00001185555,0.00003815051,0.00003442505,0.00006561635],"domain_scores_gemma":[0.9989579,0.0001240732,0.0001575032,0.00004361543,0.00007680852,0.000640025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.82664,0.02330832,0.003893184,0.001334168,0.00213278,0.0003741953,0.0002477176,0.002340475,0.01680133,0.0004911016,0.01664443,0.1057924],"study_design_scores_gemma":[0.8268802,0.1590644,0.007086011,0.00006837435,0.0005118742,0.0003323127,0.00009879418,0.001505876,0.001363168,0.0002554206,0.002789548,0.00004404096],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9814641,0.005557549,0.0007059319,0.002133833,0.0005165526,0.002748269,0.002790274,0.0001890465,0.003894456],"genre_scores_gemma":[0.9759642,0.00598539,0.00221146,0.002038277,0.0003247299,0.002197022,0.003500327,0.00006158234,0.007716934],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01097686,"threshold_uncertainty_score":0.02182591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05282090444412633,"score_gpt":0.3459315138132732,"score_spread":0.2931106093691468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}