{"id":"W1966049097","doi":"10.1016/j.jsb.2008.01.006","title":"Conformational changes accompany activation of reovirus RNA-dependent RNA transcription","year":2008,"lang":"en","type":"article","venue":"Journal of Structural Biology","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Capsid; RNA; Nucleic acid; Messenger RNA; Biophysics; Transcription (linguistics); Core protein; Conformational change; Polymerase; Chemistry; RNA polymerase; Icosahedral symmetry; Biology; Cell biology; Biochemistry; Enzyme; Crystallography; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003505199,0.0003318005,0.0003726602,0.0003212399,0.0003018671,0.000555301,0.0003596514,0.000413842,0.004946885],"category_scores_gemma":[0.001028714,0.0002928894,0.0004846673,0.0001856009,0.0004331907,0.000534659,0.0003254529,0.001169857,0.0009021427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004897644,"about_ca_system_score_gemma":0.0001568902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004554277,"about_ca_topic_score_gemma":0.0007834802,"domain_scores_codex":[0.9997064,0.00005287783,0.00001270279,0.0000545744,0.00005532202,0.0001180546],"domain_scores_gemma":[0.9992906,0.0002929178,0.0001139704,0.00009344306,0.00007478317,0.0001342355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001503634,0.0001145508,0.001728835,0.00006083,0.00004136812,0.0004533773,0.000153008,0.0004395313,0.9917209,0.0007291321,0.0003419522,0.002712837],"study_design_scores_gemma":[0.0001310986,0.0008660838,0.04916995,0.00003403848,0.00004894865,0.001148373,0.0003652585,0.004610969,0.9400325,0.001086615,0.002442692,0.00006338801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944069,0.0007399398,0.002156104,0.0002395269,0.00007978556,0.00002588475,0.0002130291,0.00005788707,0.002080841],"genre_scores_gemma":[0.9982645,0.0001278185,0.0003908314,0.000124011,0.00002213043,0.00001391124,0.0004261705,0.00001907312,0.0006116486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004946885,"threshold_uncertainty_score":0.01654899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05736275598491658,"score_gpt":0.3333493753611599,"score_spread":0.2759866193762434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}