{"id":"W1966103529","doi":"10.1038/nature10980","title":"Hsp72 preserves muscle function and slows progression of severe muscular dystrophy","year":2012,"lang":"en","type":"article","venue":"Nature","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":271,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Muscular dystrophy; ITGA7; Dystrophin; Duchenne muscular dystrophy; Heat shock protein; Muscle disorder; Sarcoplasm; Dystrophy; Endoplasmic reticulum; Dysferlin; Skeletal muscle; Medicine; Myocyte; Endocrinology; Biology; Internal medicine; Cell biology; Pathology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000803852,0.00008966561,0.00008631633,0.00001945602,0.00004864661,0.000003493438,0.00006719003,0.0007377162,0.00002378099],"category_scores_gemma":[0.00004379665,0.00007230839,0.00005053262,0.00004494672,0.00005869924,0.000008409358,0.0000722074,0.0002881588,0.000001505164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001872755,"about_ca_system_score_gemma":0.00001159151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003027515,"about_ca_topic_score_gemma":0.000002636508,"domain_scores_codex":[0.9994923,0.00004392623,0.00007994455,0.0001577474,0.00007515461,0.0001508681],"domain_scores_gemma":[0.9996642,0.000005696622,0.00005085304,0.0001855551,0.00004032052,0.00005332811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003505976,0.0001614066,0.02956418,0.0001081116,0.00006223584,2.772331e-7,0.00005210525,0.00001629296,0.955385,0.0004219554,0.003767954,0.01010993],"study_design_scores_gemma":[0.001116534,0.0006260953,0.8821905,0.00003241849,0.00005321369,0.000006264798,0.0001279269,0.00001794692,0.0529101,0.00065678,0.06200325,0.0002589968],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881869,0.01057265,0.00004765783,0.00006977115,0.0001779367,0.0001178,0.000008877814,0.000008045834,0.0008103761],"genre_scores_gemma":[0.9990978,0.0001040531,0.0002524422,0.0001596633,0.0001830698,0.00001063498,0.00008779921,0.000009134646,0.00009539816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9024748,"threshold_uncertainty_score":0.5689943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004119464579597948,"score_gpt":0.2446411611653066,"score_spread":0.2405216965857087,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}