{"id":"W1966121655","doi":"10.1038/emboj.2008.6","title":"Phosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APCCdh1 in G1 phase","year":2008,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"American Association for Cancer Research","keywords":"Biology; SKP2; Phosphorylation; Cyclin-dependent kinase; Ubiquitin ligase; Cell biology; Mitosis; Cyclin-dependent kinase 2; Phosphorylation cascade; Mitotic exit; CDH1; Cell cycle; Cyclin B; Ubiquitin; Cyclin; Protein kinase A; Biochemistry; Protein phosphorylation; Cell; Anaphase; Cadherin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001096867,0.00008670192,0.00009706026,0.00002295022,0.0000906327,0.00001116325,0.00009176617,0.00005178819,0.00001279301],"category_scores_gemma":[0.0000226104,0.00006677648,0.00002685796,0.00006881948,0.00005728761,0.000004438382,0.00002946739,0.00009358273,8.79188e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007655041,"about_ca_system_score_gemma":0.00003636532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002522614,"about_ca_topic_score_gemma":0.00000987459,"domain_scores_codex":[0.999404,0.0000605529,0.000208225,0.0001226869,0.00009853185,0.0001059744],"domain_scores_gemma":[0.9997156,0.000007347182,0.0001195784,0.00009155837,0.0000265582,0.00003930722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009306403,0.00008628972,0.0004187636,0.000003952893,0.00002174407,0.000001767325,0.0001870729,0.00001599148,0.9829983,0.000001078859,0.003141051,0.01303092],"study_design_scores_gemma":[0.002515867,0.0003348545,0.008603703,0.00004053938,0.00001826928,0.0001075634,0.000146274,0.0002449241,0.9725868,0.0002397356,0.01496957,0.0001918897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855539,0.01369999,0.0003505207,0.0001523114,0.00003033465,0.0001397398,0.00001395019,0.000001677204,0.00005755566],"genre_scores_gemma":[0.982143,0.01741393,0.0001548627,0.00007231502,0.000009461018,0.000004428955,0.000073558,0.000009974317,0.0001184949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01283903,"threshold_uncertainty_score":0.2723066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01022074807960707,"score_gpt":0.2295576382043413,"score_spread":0.2193368901247342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}