{"id":"W1966136677","doi":"10.1016/j.bmc.2013.05.062","title":"Synthesis of 4-methylumbelliferyl α-d-mannopyranosyl-(1→6)-β-d-mannopyranoside and development of a coupled fluorescent assay for GH125 exo-α-1,6-mannosidases","year":2013,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Victoria; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Simon Fraser University; Michael Smith Health Research BC","keywords":"Disaccharide; Chemistry; Glycoside hydrolase; Enzyme; Virulence; Glycan; Glycoconjugate; Biochemistry; Stereochemistry; Glycoside; Glycoprotein; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003317631,0.0009268766,0.0005348659,0.0004999264,0.0003561124,0.0002982936,0.0006474609,0.0004208445,0.00250182],"category_scores_gemma":[0.0002608745,0.000316287,0.0004602546,0.0005081822,0.0002199001,0.0003121188,0.0004080203,0.0007943356,0.001815437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005193197,"about_ca_system_score_gemma":0.0007163532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001202998,"about_ca_topic_score_gemma":0.001829577,"domain_scores_codex":[0.9997647,0.00004371023,0.000019323,0.000036034,0.00004729219,0.00008893268],"domain_scores_gemma":[0.9998492,0.00002210477,0.00002499224,0.00002544292,0.00002658549,0.00005161577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002224409,0.0001108765,0.0001550162,0.0001320364,0.00001900093,0.0002703606,0.00008805149,0.001362407,0.9853132,0.001346291,0.0002650769,0.01071521],"study_design_scores_gemma":[0.00002667724,0.0003466903,0.0004200703,0.000005780418,0.00001227353,0.0001295755,0.00001761567,0.0005565336,0.992527,0.0001349083,0.005806986,0.00001586258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8521116,0.002497198,0.1245307,0.0004204712,0.0001923215,0.0009432234,0.004551161,0.001139867,0.01361355],"genre_scores_gemma":[0.8939808,0.001826025,0.0849319,0.0001205794,0.00004030808,0.0004825155,0.006084619,0.0001292875,0.01240395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00250182,"threshold_uncertainty_score":0.008369386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01467057654526584,"score_gpt":0.2256470507848265,"score_spread":0.2109764742395606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}