{"id":"W1966162777","doi":"10.1097/jto.0b013e3181f49c22","title":"Efficacy and Safety of Bevacizumab-Based Therapy in Elderly Patients with Advanced or Recurrent Nonsquamous Non-small Cell Lung Cancer in the Phase III BO17704 Study (AVAiL)","year":2010,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Bevacizumab; Medicine; Gemcitabine; Placebo; Clinical endpoint; Hazard ratio; Internal medicine; Lung cancer; Oncology; Phases of clinical research; Chemotherapy; Surgery; Gastroenterology; Randomized controlled trial; Confidence interval; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004738527,0.0001625239,0.0005570406,0.0002289328,0.00005155804,0.000008463531,0.0001320117,0.00008532453,0.00006355106],"category_scores_gemma":[0.00004061022,0.0000835495,0.00005046587,0.0002811791,0.0000724786,0.00007777233,0.00001228468,0.000547061,2.592377e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002372814,"about_ca_system_score_gemma":0.001034152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00011193,"about_ca_topic_score_gemma":0.002439997,"domain_scores_codex":[0.9985974,0.0001686313,0.0006181585,0.0001698159,0.0002498366,0.0001961013],"domain_scores_gemma":[0.9986084,0.0002897964,0.0005676858,0.0001957444,0.0002468626,0.00009155284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.07959852,0.01859509,0.1894501,0.00008964241,0.000202159,0.0003184341,0.01025279,0.0002129226,0.0009011179,9.141043e-7,0.00006856485,0.7003098],"study_design_scores_gemma":[0.1681222,0.07529889,0.7482314,0.0005028188,0.001002457,0.00006487092,0.003293936,0.0002108475,0.0007825705,0.000005544552,0.002271149,0.0002133309],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961955,0.000580608,0.00004917189,0.0006836304,0.0003009368,0.002016724,0.00001728798,0.000003028911,0.0001531015],"genre_scores_gemma":[0.998489,0.0002159676,0.0009622349,0.000149769,0.00005875877,0.00007235934,0.00000583416,0.00001563253,0.00003042311],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7000964,"threshold_uncertainty_score":0.340705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01408119831461073,"score_gpt":0.4202527993054573,"score_spread":0.4061716009908466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}