{"id":"W1966177375","doi":"10.1182/blood-2002-06-1918","title":"Hematopoietic stem cell and progenitor defects in Sca-1/Ly-6A–null mice","year":2002,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":187,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Mount Sinai Hospital; University of Toronto; Ontario Institute for Cancer Research","funders":"National Institutes of Health; Canadian Institutes of Health Research; Terry Fox Foundation; Leukemia and Lymphoma Society","keywords":"Haematopoiesis; Bone marrow; Stem cell; Biology; Megakaryocyte; Progenitor cell; Immunology; Molecular biology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000323829,0.001131561,0.0005945618,0.002395415,0.0004494016,0.0006473918,0.0008006537,0.001366964,0.004234373],"category_scores_gemma":[0.0002223935,0.0005734406,0.000558985,0.0004924069,0.000903152,0.0004656556,0.0005183576,0.001887342,0.001352223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003823105,"about_ca_system_score_gemma":0.0003446856,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005323967,"about_ca_topic_score_gemma":0.0009351341,"domain_scores_codex":[0.9994266,0.00005829091,0.00008291995,0.0001675935,0.0001917396,0.00007291667],"domain_scores_gemma":[0.9992085,0.00007081772,0.000339637,0.00005031182,0.00003913542,0.000291622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001532373,0.00007980179,0.0003812721,0.00004291199,0.00001168319,0.0002699114,0.00004917627,0.0001283659,0.9965034,0.0004814406,0.00009857355,0.001800415],"study_design_scores_gemma":[0.0001890199,0.0008887655,0.01717652,0.00009153489,0.0001022001,0.005093994,0.0001273169,0.00331881,0.9644475,0.0007398487,0.007777301,0.00004719525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787295,0.002533426,0.00940861,0.0002643857,0.00006936485,0.0001626429,0.005275842,0.0009280409,0.002628169],"genre_scores_gemma":[0.9584951,0.002779591,0.0170213,0.0002106338,0.00006679462,0.0003677543,0.005709751,0.0005078272,0.01484118],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004234373,"threshold_uncertainty_score":0.0141654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01570773193844599,"score_gpt":0.2227394937918667,"score_spread":0.2070317618534207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}