{"id":"W1966217582","doi":"10.1007/s00262-004-0572-2","title":"Antibody-targeted chemotherapy of B-cell lymphoma using calicheamicin conjugated to murine or humanized antibody against CD22","year":2004,"lang":"en","type":"article","venue":"Cancer Immunology Immunotherapy","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Calicheamicin; CD22; Conjugate; Antibody; Monoclonal antibody; Epitope; Saporin; Linker; Chemistry; Immunotoxin; Humanized antibody; Molecular biology; Biochemistry; Cancer research; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002070868,0.0002767663,0.0004068338,0.0003271711,0.0002191564,0.0003293935,0.0003220494,0.0003646062,0.0007505553],"category_scores_gemma":[0.0002098181,0.0001346464,0.0001647195,0.0003766704,0.0001862464,0.0002132581,0.0003051647,0.0005011134,0.0001816041],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006353242,"about_ca_system_score_gemma":0.0004146512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001773717,"about_ca_topic_score_gemma":0.003919931,"domain_scores_codex":[0.9999026,0.00002124502,0.000004311888,0.00001435195,0.00002293822,0.00003457845],"domain_scores_gemma":[0.9999502,0.00001144056,0.00000835909,0.000009993641,0.000005974833,0.00001414351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002443213,0.0009108314,0.001952743,0.0003089302,0.0001687524,0.0006200699,0.0001722347,0.00876852,0.8894629,0.003920936,0.002293082,0.08897775],"study_design_scores_gemma":[0.002116597,0.007807282,0.008938625,0.00004376824,0.0001969694,0.00189513,0.00005424485,0.01597455,0.940417,0.0004478676,0.02208019,0.0000277974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839087,0.004546311,0.005176222,0.0003006568,0.0001120481,0.000162628,0.0001019309,0.0001772784,0.005514326],"genre_scores_gemma":[0.9952067,0.001471594,0.001694443,0.00007390522,0.0000124313,0.00004774679,0.0001212695,0.00001508452,0.00135679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001773717,"threshold_uncertainty_score":0.004609644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03108353627508348,"score_gpt":0.366271566943155,"score_spread":0.3351880306680716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}