{"id":"W1966249219","doi":"10.1111/j.1399-0004.2007.00844_1.x","title":"SORL1 adds another piece to the complex puzzle of Alzheimer disease genetics","year":2007,"lang":"en","type":"article","venue":"Clinical Genetics","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Genetics; Biology; Alzheimer's disease; Disease; Molecular genetics; Degenerative disease; Neuroscience; Medicine; Gene; Central nervous system disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006567785,0.0002057571,0.0003974029,0.00006860979,0.0001019689,0.000015524,0.0002726318,0.0001093308,0.0004542572],"category_scores_gemma":[0.0002986488,0.0001378535,0.0003039988,0.0002734126,0.0004007995,0.00001364452,0.0001867346,0.0002182108,0.0004292543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002120571,"about_ca_system_score_gemma":0.0002483907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008270773,"about_ca_topic_score_gemma":0.00002632948,"domain_scores_codex":[0.9975897,0.0001169011,0.0007562034,0.0003871188,0.0006242273,0.0005258452],"domain_scores_gemma":[0.9971423,0.0003897092,0.0001216224,0.000972816,0.0002723924,0.001101208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002685625,0.004369262,0.8090645,0.00007098434,0.00795369,0.0003291271,0.0001470082,0.00009405923,0.0003017401,0.0001354157,0.03935847,0.1354901],"study_design_scores_gemma":[0.001788834,0.0008082242,0.932359,0.00003855106,0.001464614,0.000004236087,0.00004263526,0.0003666473,0.001291987,0.0001332197,0.06153832,0.0001637776],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9475698,0.03815298,0.001906668,0.004777744,0.0004264723,0.00226843,0.000253187,0.00007294353,0.004571774],"genre_scores_gemma":[0.9915273,0.0008921021,0.003973027,0.002703053,0.0005859666,0.00001753085,0.00005538414,0.00005165944,0.0001940201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1353263,"threshold_uncertainty_score":0.5621504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1861043667146587,"score_gpt":0.4564015056592848,"score_spread":0.2702971389446261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}