{"id":"W1966369277","doi":"10.1503/cmaj.131582","title":"Regulatory decisions pertaining to aprotinin may be putting patients at risk","year":2014,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"Blood transfusion and management","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"Medicines Company; AstraZeneca","keywords":"Aprotinin; Antifibrinolytic; Tranexamic acid; Aminocaproic acid; Serine protease; Medicine; Protease inhibitor (pharmacology); Pharmacology; Anesthesia; Surgery; Protease; Chemistry; Biochemistry; Immunology; Blood loss; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02138167,0.0004153358,0.000647327,0.0005931705,0.002784304,0.007058771,0.001622178,0.01228172,0.009575295],"category_scores_gemma":[0.08842011,0.00029082,0.0009862699,0.0007671261,0.004705964,0.003596076,0.002185783,0.01533074,0.002820084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002634662,"about_ca_system_score_gemma":0.01015299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002274735,"about_ca_topic_score_gemma":0.005486146,"domain_scores_codex":[0.9825749,0.00767308,0.001790226,0.00116104,0.005711874,0.001088787],"domain_scores_gemma":[0.9523773,0.02469211,0.007638756,0.00217577,0.008376516,0.004739437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008180654,0.0004213099,0.01462279,0.0005288264,0.0001748224,0.004476951,0.002334117,0.001234048,0.003816307,0.1654349,0.526414,0.2797239],"study_design_scores_gemma":[0.0001738716,0.0004313731,0.004591711,0.001658664,0.0001251041,0.004045018,0.002069802,0.0007321977,0.002315052,0.1000289,0.8836882,0.0001400405],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01056128,0.008540079,0.005070701,0.9090166,0.009913238,0.00006003723,0.0001057613,0.0001638386,0.05656846],"genre_scores_gemma":[0.2012904,0.01507815,0.009815911,0.7372652,0.02649056,0.000102045,0.0003045864,0.000196395,0.009456745],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02138167,"threshold_uncertainty_score":0.1130785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009699706770257272,"score_gpt":0.2389013790802208,"score_spread":0.2292016723099635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}