{"id":"W1966400763","doi":"10.1016/s0168-1656(00)00313-8","title":"Vaccine delivery: lipid-based delivery systems","year":2000,"lang":"en","type":"review","venue":"Journal of Biotechnology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Luonnontieteiden ja Tekniikan Tutkimuksen Toimikunta; Medical Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Transdermal; Delivery system; Mucosal immunity; DNA vaccination; Immunity; Medicine; Immunization; Immunology; Immune system; Pharmacology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0007436923,0.0007440576,0.003780044,0.002008387,0.0002017221,0.00003943937,0.001489123,0.003837469,0.0008327503],"category_scores_gemma":[0.0001177919,0.0005466609,0.001359729,0.0006441395,0.0003079747,0.0001225117,0.0001048426,0.002633051,0.0008394944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002532587,"about_ca_system_score_gemma":0.001047289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005166227,"about_ca_topic_score_gemma":0.000002897381,"domain_scores_codex":[0.9955859,0.001032963,0.00220649,0.0003968975,0.00009219514,0.0006856007],"domain_scores_gemma":[0.9960695,0.0006219229,0.002266085,0.0008461915,0.000161709,0.00003460502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008007065,0.0002351877,0.000001292989,0.001627289,0.001549052,0.0001473195,0.00001483262,0.000006539486,0.002581436,0.00006813623,0.009252304,0.9837159],"study_design_scores_gemma":[0.001716718,0.001282864,0.000001762661,0.0077447,0.001120116,0.005671237,0.0000291074,7.925781e-7,0.002117264,0.000004866618,0.9798274,0.0004831479],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007338968,0.99496,0.00007124645,0.000192989,0.003318146,0.0004729017,0.00006892932,0.0001182516,0.00006362496],"genre_scores_gemma":[0.0003556632,0.9977514,0.00006079291,0.00009095792,0.0001949625,0.00001930961,0.00006706128,0.00009552541,0.001364338],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9832327,"threshold_uncertainty_score":0.9999385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01930555954594581,"score_gpt":0.26561979833132,"score_spread":0.2463142387853742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}