{"id":"W1966418219","doi":"10.1016/j.neuron.2006.12.020","title":"Calpain-Mediated mGluR1α Truncation: A Key Step in Excitotoxicity","year":2007,"lang":"en","type":"article","venue":"Neuron","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":162,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Excitotoxicity; Neuroprotection; Metabotropic glutamate receptor; Metabotropic glutamate receptor 1; Glutamate receptor; Calpain; NMDA receptor; Neuroscience; Ionotropic effect; Cell biology; Long-term depression; Biology; Metabotropic glutamate receptor 5; Chemistry; Receptor; Pharmacology; Biochemistry; AMPA receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007595829,0.0001986104,0.0001978601,0.0004163998,0.0001978056,0.00005466494,0.0006163192,0.00009509279,0.0001467497],"category_scores_gemma":[0.001771793,0.0001918821,0.00005835102,0.001558874,0.0003351365,0.0003036217,0.0001601811,0.0006972669,0.0004425844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006790813,"about_ca_system_score_gemma":0.00009937747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000244898,"about_ca_topic_score_gemma":0.00004676911,"domain_scores_codex":[0.9968414,0.0004270898,0.0003761225,0.0008318987,0.000656176,0.0008672624],"domain_scores_gemma":[0.9980024,0.001264308,0.00008438411,0.0003602957,0.00003531106,0.0002533299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001422024,0.0002117645,0.005013502,0.000008868108,3.097634e-7,0.0009602748,0.00009000592,0.00001032691,0.9912317,0.0001929078,0.0005685742,0.001569504],"study_design_scores_gemma":[0.001101221,0.0003569416,0.09133845,0.00000781691,0.000002184203,0.00008590611,0.00001794623,0.001743332,0.8878436,0.0000547879,0.01722252,0.0002252596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937336,0.00001102019,0.00009747017,0.0009592663,0.0007694512,0.0004840987,0.000006904338,0.0001477685,0.003790377],"genre_scores_gemma":[0.9921071,0.00007504964,0.00001458441,0.0068197,0.0001252196,0.00002473163,6.459722e-7,0.00002869047,0.0008042729],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1033881,"threshold_uncertainty_score":0.7824726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05478028773848315,"score_gpt":0.3515297259080839,"score_spread":0.2967494381696008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}