{"id":"W1966447073","doi":"10.1074/jbc.m209470200","title":"Structure-Function Relationship between the Human Chemokine Receptor CXCR3 and Its Ligands","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":191,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Arthritis Society; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"CXCR3; Chemokine receptor; C-C chemokine receptor type 6; Chemokine; CCL21; CCL25; Function (biology); Cell biology; Receptor; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002571927,0.0001270925,0.0002963658,0.00002068787,0.0001295721,0.00001981271,0.00008767544,0.000234512,0.001300977],"category_scores_gemma":[0.0004822767,0.00006673287,0.000121734,0.0001225848,0.00007065768,0.0000414038,0.00003001353,0.0006150139,0.000003279332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004287684,"about_ca_system_score_gemma":0.00001016731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":2.91568e-7,"about_ca_topic_score_gemma":2.367009e-8,"domain_scores_codex":[0.9991251,0.00001684528,0.0004026659,0.000127494,0.000188096,0.0001398399],"domain_scores_gemma":[0.999171,0.0002057695,0.0002668977,0.00009514627,0.0001198722,0.0001413347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004006954,0.00003552176,0.2200182,0.00004379405,0.00005256153,0.000004623919,0.00003756342,7.240574e-7,0.7774647,0.00001533169,0.001481201,0.0008056466],"study_design_scores_gemma":[0.001234018,0.0003385156,0.1441914,0.000112448,0.0001510354,0.0003225052,0.00006533966,0.00002014865,0.8481694,0.0005406663,0.004716054,0.0001384089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961241,0.001614055,0.00001913771,0.001531694,0.0000532915,0.00005467191,0.000005675722,0.00001318951,0.0005841224],"genre_scores_gemma":[0.997526,0.00009927955,0.00006912337,0.0001087453,0.001721126,7.107403e-7,0.0000159274,0.000007938565,0.0004511619],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07582675,"threshold_uncertainty_score":0.999612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06163289916865489,"score_gpt":0.2801743551149015,"score_spread":0.2185414559462466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}