{"id":"W1966470342","doi":"10.1006/abbi.2000.2026","title":"Expression and Functional Characterization of Human Protein X Variants in SV40-Immortalized Protein X-Deficient and E2-Deficient Human Skin Fibroblasts","year":2000,"lang":"en","type":"article","venue":"Archives of Biochemistry and Biophysics","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Medical Research Council","keywords":"Mutant; Autophagy-related protein 13; Pyruvate dehydrogenase complex; Biology; Mutant protein; Transfection; Gene; Molecular biology; Biochemistry; Wild type; Saccharomyces cerevisiae; Chemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002908674,0.0004049929,0.0002185448,0.0003084351,0.0002314663,0.0004157943,0.0002519846,0.0002722789,0.001139897],"category_scores_gemma":[0.0002107498,0.000200718,0.0003949546,0.0002780363,0.0002228481,0.0002952263,0.0002172609,0.0004055885,0.0006549603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001887271,"about_ca_system_score_gemma":0.0001437186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009806593,"about_ca_topic_score_gemma":0.0006305129,"domain_scores_codex":[0.9998178,0.00003200129,0.0000353553,0.00003938952,0.00004013807,0.00003529766],"domain_scores_gemma":[0.9997779,0.00007444328,0.00002811455,0.00005335138,0.00002804321,0.00003827311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006088992,0.00001129523,0.0001161255,0.00001108099,0.000003064365,0.00006637065,0.0000234692,0.00002205476,0.9992859,0.00007783187,0.000009373915,0.0003125481],"study_design_scores_gemma":[0.00000836679,0.00008854052,0.003983253,0.000002528438,0.00001502256,0.0005905782,0.00004951506,0.0003542778,0.993413,0.0000435531,0.001447196,0.000004120374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913891,0.00120157,0.005012562,0.00004912784,0.00002483107,0.00003041757,0.001017695,0.00006664928,0.001208076],"genre_scores_gemma":[0.9847371,0.001044127,0.004407573,0.00003639647,0.00001525699,0.00003494731,0.003080701,0.00007024549,0.006573562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001139897,"threshold_uncertainty_score":0.003813386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007285650116020312,"score_gpt":0.2301041583096518,"score_spread":0.2228185081936314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}