{"id":"W1966494491","doi":"10.1016/j.ddmec.2006.11.008","title":"Role of PML/RARα in the pathogenesis of APL","year":2006,"lang":"en","type":"article","venue":"Drug Discovery Today Disease Mechanisms","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Pathogenesis; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008977709,0.0004617333,0.0005077239,0.00107864,0.0005136418,0.00137222,0.0005022022,0.0006983691,0.001193266],"category_scores_gemma":[0.000414406,0.0002383598,0.000341332,0.0003331091,0.001177379,0.000718231,0.000392833,0.001216796,0.0005793176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001112992,"about_ca_system_score_gemma":0.0007376106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006326118,"about_ca_topic_score_gemma":0.0004893687,"domain_scores_codex":[0.999665,0.0001281346,0.00003579792,0.00003449383,0.00007670385,0.00005982362],"domain_scores_gemma":[0.9997396,0.00006823862,0.00006372968,0.00004297448,0.00003705154,0.00004834244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003087367,0.0001825384,0.005309233,0.0009352932,0.0001134717,0.005125864,0.0003360656,0.002018779,0.823741,0.03193213,0.001850059,0.1253683],"study_design_scores_gemma":[0.0003721592,0.001409013,0.01396871,0.0002625914,0.0002664447,0.01706432,0.0005045286,0.001968737,0.838213,0.02612938,0.09978306,0.00005809165],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.4029242,0.540978,0.01871951,0.01291794,0.0004779044,0.0000865768,0.0003962473,0.0005236728,0.02297599],"genre_scores_gemma":[0.9059359,0.08228053,0.004223105,0.0003902806,0.0002937478,0.0000222711,0.0001181925,0.00002111781,0.006714738],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00137222,"threshold_uncertainty_score":0.008075416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002784583957802258,"score_gpt":0.1938494848493849,"score_spread":0.1910649008915826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}